Purchase this article with an account.
C. C. Farias, L. B. Souza, L. A. Vieira, N. Alleman, J. A. P. Gomes; Comparison Amongst Corneal and Amniotic Membranne Grafts to Restore Corneal Thinning. Invest. Ophthalmol. Vis. Sci. 2009;50(13):1516.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
To evaluate the efficacy of multilayer amniotic membrane transplantation compared with corneal path for repairing corneal thinning after infection, immunologic diseases or ocular surgery.
Prospective, comparative, interventional study of nineteen eyes of nineteen patients with corneal thinning after infection or ocular surgery. The mean age was 63,9 years old (range 47-83 years). Eight patients (42%) were female and 11 (58%) male. All patients were operated by the same surgeon and the surgical procedure was randomized in corneal or amniotic membrane graft. Ten patients underwent surgery with corneal graft (52%) and nine with amniotic membrane transplantation (48%). Patients were followed for 180 days.
All the eyes that received corneal grafts presented stability of the ocular surface with rapid reepithelialization; on the other hand, most of the eyes that received the amniotic membrane grafts had the transplanted tissue reabsorbed after approximately 30d of the surgery (%). There were a few complications: two patients who underwent surgery with corneal patch (20%) presented corneal graft rejection that was controlled with steroids. Three patients needed to be reoperated: two patients (20%) who underwent corneal graft and one patient (11%) who underwent amniotic membrane transplantation.
Our results suggest that both amniotic membrane and corneal grafts are good options to be used for restoring corneal defects with thinning.
Clinical Trial: :
This PDF is available to Subscribers Only