Abstract
Purpose: :
To evaluate the success of chemoreduction for group E retinoblastoma (Rb).
Methods: :
Retrospective chart review
Results: :
Of the 64 eyes in the chemoreduction (CRD) group 25% were salvaged with CRD alone and 20% with CRD and therapeutic [standard dose] external beam radiation (T-EBRT), while 34% were enucleated following CRD alone and 20% following CRD+T-EBRT. Of the 12 eyes in the CRD + prophylactic [low dose] external beam radiation (P-EBRT) group, 83% were salvaged with CRD+P-EBRT, while 17% were enucleated and none required T-EBRT.
Keywords: clinical (human) or epidemiologic studies: outcomes/complications • tumors • retina