Abstract
Purpose: :
To assess the effects of intravitreal bevacizumab (Avastin) injections in the treatment of choroideal neovascularization (CNV) associated with multifocal choroiditis (MC).
Methods: :
Prospective interventional case series. Patients with MC complicated by subfoveal CNV underwent a complete ophthalmologic examination, including ETDRS visual acuity, optical coherence tomography (OCT), fluorescein angiography, and indocyanine green angiography. The protocol required 3 monthly consecutive injections, followed by repeated injections as needed. The planned follow-up was 12 months.
Results: :
Ten patients were enrolled in the study and prospectively followed up. Mean visual acuity and mean foveal thickness (FT) at the baseline were 0.58±0.48 (logMAR±SD) and 290±92µm SD, respectively. At the 3-month examination, mean visual acuity improved to 0.42±0.48 and mean FT decreased to 298±172µm SD. At the 12-month examination, mean visual acuity was 0.40±0.49, and mean FT was 255±163µm. No side-effect or complication was registered.
Keywords: choroid: neovascularization • chorioretinitis