April 2009
Volume 50, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2009
Femtosecondlaser Assisted Penetrating Keratoplasty - First Clinical Results
Author Affiliations & Notes
  • F. Birnbaum
    Univ Eye Hospital Freiburg, Germany, Freiburg, Germany
  • A. Wiggermann
    Univ Eye Hospital Freiburg, Germany, Freiburg, Germany
  • D. Böhringer
    Univ Eye Hospital Freiburg, Germany, Freiburg, Germany
  • P. Maier
    Univ Eye Hospital Freiburg, Germany, Freiburg, Germany
  • T. Reinhard
    Univ Eye Hospital Freiburg, Germany, Freiburg, Germany
  • Footnotes
    Commercial Relationships  F. Birnbaum, None; A. Wiggermann, None; D. Böhringer, None; P. Maier, None; T. Reinhard, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science April 2009, Vol.50, 2199. doi:
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      F. Birnbaum, A. Wiggermann, D. Böhringer, P. Maier, T. Reinhard; Femtosecondlaser Assisted Penetrating Keratoplasty - First Clinical Results. Invest. Ophthalmol. Vis. Sci. 2009;50(13):2199.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : Functional results of penetrating keratoplasty are often impaired by postoperative astigmatism. This is due to inadequacy of trephination, suturing, astigmatism of the donor and wound healing. A promising new approach is the femtosecondlaser assisted penetrating keratoplasty. Different laser profiles like the tophat- or the mushroom-profile may be performed using this technique.

Methods: : We performed 26 mushroom-keratoplasties and 42 tophat-keratoplasties to date. Mean follow-up is 3.3 months. We used the tophat-profile in patients with Fuchs endothelial dystrophy, bullous keratopathy and keratoconus. The mushroom-profile was used exclusively in patients with keratoconus. The side cut differed between 1.0mm and 2.0mm, resulting in an overlap of 0.5mm or 1.0mm, respectively.

Results: : The average best corrected visual acuity is 10/20 in the mushroom group and 6/30 in the tophat group. All patients have at least one running suture left.The postoperative astigmatism in Orbscan topography was 6.5±4.4 diopters (mean±standard deviation) in the mushroom group and 5.0±3.0 diopters in the tophat group.

Conclusions: : Femtosecondlaser assisted penetrating keratoplasty allows for new trephination profiles with a larger stromal contact surface between graft and recipient. Therefore a higher wound stability can be supposed. This might lead to an earlier suture removal and possibly to a better refractive outcome. Our current results are obtained in an early postoperative stage with predominantly 2 or 1 running sutures in. The benefits from this technique will most likely reveal only after complete suture removal.

Keywords: cornea: clinical science • laser • transplantation 
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