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F. May, J.-M. Giraud, K. Reda, J.-R. Fenolland, R. Dariel, J.-F. Maurin, J.-P. Renard; Analysis of a New Visual Field Index VFI in Open Angle Glaucoma (OAG) and Intra-Ocular Hypertonia (IOHT). Invest. Ophthalmol. Vis. Sci. 2009;50(13):2224.
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© ARVO (1962-2015); The Authors (2016-present)
Visual Field Index VFI is a new perimetric index allowing evaluation of visual function level and progression in OAG. Expressed in percentage, VFI is evaluated from the age corrected defect depth of each test-point of successive pattern deviation probability maps.
Retrospective study on 94 eyes: 35 IOHT, 34 early OAG (0>MD>-6), 13 moderate OAG (-6>MD>-12) and 12 advanced OAG (MD<-12), with a mean follow-up of 6,5 years (4 to 8 years). Each subject perfomed a mean number of 10 SAP visual field tests (Humphrey SITA Standard 24.2), excluding tests without reliable indices. Analysis concerns: VFI progression rate and curve aspect, predictibility of further evolution at follow-up meantime, and correlation with alert signals (likely or probable evolution) of the GPA2 Glaucoma Progression Analysis .
IOHT: VFI stability during the follow-up with a predictibility at 3 years noted in 97% of eyes; concordance with GPA2 results in 97% of cases. Early OAG: stable VFI: 88%; predictibility: 76%; no progression detected by GPA2 in 76% of eyes; VFI-GPA2 concordance in 85% of cases. Moderate OAG: stable VFI in 31% of eyes; predictibility:70%; no progression detected by GPA2: 54%; VFI-GPA2 concordance: 85%. Advanced OAG: stable VFI only in 33% of eyes; predictibility: 75%. GPA2 could not be performed in very advanced OAG with large and deep defects (30% of subjects), where VFI can be evaluated. When allowed, VFI and GPA2 concordance were present in 87% of eyes. These results point out a good VFI predictibility at 3-years follow-up, with a comparable value in all OAG subjects in this study. The authors discuss about the usefullness of VFI in OAG and about the concordance between VFI and GPA2.
VFI appears to be a complementary and reliable index for OAG follow-up survey, usefull in each evolution stage, particularly in advanced OAG and in case of recent progression, when GPA2 statistic analysis is not allowed. Predictibility at 3-years follow-up seems to be good but must be confirmed by studies with more subjects.
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