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J. Yoon, S. J. Lee, H. J. Koh, S. C. Lee, O. W. Kwon; Visual Outcome After PDT and Intravitreal Anti-VEGF Injection for Myopic CNV. Invest. Ophthalmol. Vis. Sci. 2009;50(13):2275.
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© ARVO (1962-2015); The Authors (2016-present)
To compare visual outcome after PDT and intravitreal anti-VEGF injection for subfoveal myopic CNV.
Retrospective review of medical records of 140 subfoveal myopic CNV patients (157 eyes) either treated with PDT and/or intravitreal anti-VEGF were performed and categorized into 3 subgroups of PDT (59 cases), anti-VEGF (72 cases), combination of PDT and anti-VEGF (32 cases). Baseline best corrected visual acuity, 3, 6, 9, 12 months after treatment were compared.
PDT and combination group showed no significant differences between baseline and postoperative visual acuity at every follow-up (P>0.05). Anti-VEGF group showed visual improvement compared to baseline visual acuity at 6, 9, 12 months after treatment. (P=0.021, 0.015, 0.003 respectively). Anti-VEGF group showed significant postoperative visual improvement from baseline vision compared to PDT and combination group at 12 months (P=0.006).
Intravitreal anti-VEGF injection is superior to PDT alone or combination of both in subfoveal myopic CNV.
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