April 2009
Volume 50, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2009
Visual Outcome After PDT and Intravitreal Anti-VEGF Injection for Myopic CNV
Author Affiliations & Notes
  • J. Yoon
    Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Republic of Korea
  • S. J. Lee
    Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Republic of Korea
  • H. J. Koh
    Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Republic of Korea
  • S. C. Lee
    Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Republic of Korea
  • O. W. Kwon
    Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Republic of Korea
  • Footnotes
    Commercial Relationships  J. Yoon, None; S.J. Lee, None; H.J. Koh, None; S.C. Lee, None; O.W. Kwon, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science April 2009, Vol.50, 2275. doi:
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      J. Yoon, S. J. Lee, H. J. Koh, S. C. Lee, O. W. Kwon; Visual Outcome After PDT and Intravitreal Anti-VEGF Injection for Myopic CNV. Invest. Ophthalmol. Vis. Sci. 2009;50(13):2275.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To compare visual outcome after PDT and intravitreal anti-VEGF injection for subfoveal myopic CNV.

Methods: : Retrospective review of medical records of 140 subfoveal myopic CNV patients (157 eyes) either treated with PDT and/or intravitreal anti-VEGF were performed and categorized into 3 subgroups of PDT (59 cases), anti-VEGF (72 cases), combination of PDT and anti-VEGF (32 cases). Baseline best corrected visual acuity, 3, 6, 9, 12 months after treatment were compared.

Results: : PDT and combination group showed no significant differences between baseline and postoperative visual acuity at every follow-up (P>0.05). Anti-VEGF group showed visual improvement compared to baseline visual acuity at 6, 9, 12 months after treatment. (P=0.021, 0.015, 0.003 respectively). Anti-VEGF group showed significant postoperative visual improvement from baseline vision compared to PDT and combination group at 12 months (P=0.006).

Conclusions: : Intravitreal anti-VEGF injection is superior to PDT alone or combination of both in subfoveal myopic CNV.

Keywords: choroid: neovascularization • myopia 
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