Abstract
Purpose: :
To evaluate the imaging ability for sub-clinical uveal effusion in primary angle closure eyes by anterior segment OCT (AS-OCT) and to compare it with ultrasound biomicroscope (UBM).
Methods: :
23 consecutive eyes with acute or chronic primary angle closure (PAC), PAC suspect (PACS), or with glaucoma (PACG) and demonstrating uveal effusion on AS-OCT or UBM were summarized. The images were evaluated and graded by masked observers. Uveal effusion was diagnosed when the suprachoroidal space was visualized as a separation between the sclera and pars plana of the ciliary body. Uveal effusion was graded as 0 (none), 1 (slit), 2 (band), and 3 (severe) as previously reported.
Results: :
In 4 eyes of 4 patients with acute PAC, 3 eyes had grade 2 and 1 eye had grade 1 uveal effusion. All 4 eyes had effusion circumferentially and were identified by both UBM and AS-OCT. Grade 1 uveal effusion was diagnosed by AS-OCT in 19 chronic PAC eyes, and 14 eyes out of these 19 eyes showed effusion on UBM; none of the effusions were seen on UBM alone. Using AS-OCT, effusion was evident in 4 quadrants (3 eyes), 3 quadrants (7 eyes), 2 quadrants (5 eyes), and 1 quadrant (4 eyes). UBM showed effusion in 3 quadrants (5 eyes), 2 quadrants (2 eyes) and 1quadrant (7 eyes). Using UBM none of the eyes demonstrated effusion in all 4 quadrants and effusion was not found in 5 eyes (P=0.015, chi-square test, William's correction).
Conclusions: :
AS-OCT seems to have greater ability compared to UBM to demonstrate sub-clinical uveal effusion, such as that present in eyes with chronic PAC.
Keywords: anterior chamber • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • uvea