Purchase this article with an account.
G. L. Spaeth, G. M. Donaire, S. G. Li; Dose, Effects and Characteristics of Pilocarpine. Invest. Ophthalmol. Vis. Sci. 2009;50(13):2482.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
I- Treatment with pilocarpine in all concentrations greater than 0.5% had a highly significant lowering effect on IOP when compared with no treatment. Two groups were identified, those with and those without a significant IOP decrease. Pilocarpine concentration up to 8% did not lower IOP in the unresponsive group.II- Four times daily administration resulted in significantly lower IOP than daily or twice daily. Twice daily treatment was slightly more effective than daily treatment. A single daily dose caused a lowering of IOP of about 4 mmHg that lasted over 24 hours. Fifty nine hours after the last dose there was no evident effect.
Clinical Trial: :
This PDF is available to Subscribers Only