April 2009
Volume 50, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2009
A Comparison Between Microperimetry and Standard Achromatic Perimetry in Glaucomatous Patients With Central Scotomas
J. H. Kim; T. S. Prata; V. C. Lima; C. G. V. DeMoreas; S. Dorairaj; W. Seiple; R. Rosen; J. M. Liebmann; R. Ritch
Author Affiliations & Notes
  • J. H. Kim
    Ophthalmology,
    The New York Eye and Ear Infirmary, New York, New York
  • T. S. Prata
    Ophthalmology,
    The New York Eye and Ear Infirmary, New York, New York
    Ophthalmology, Einhorn Clinical Research Center, New York, New York
  • V. C. Lima
    Ophthalmology,
    The New York Eye and Ear Infirmary, New York, New York
    Ophthalmology, Einhorn Clinical Research Center, New York, New York
  • C. G. V. DeMoreas
    Ophthalmology,
    The New York Eye and Ear Infirmary, New York, New York
    Ophthalmology, Einhorn Clinical Research Center, New York, New York
  • S. Dorairaj
    Ophthalmology,
    The New York Eye and Ear Infirmary, New York, New York
    Ophthalmology, Einhorn Clinical Research Center, New York, New York
  • W. Seiple
    Ophthalmology,
    The New York Eye and Ear Infirmary, New York, New York
    Ophthalmology, New York University School of Medicine, New York, New York
  • R. Rosen
    Ophthalmology, Retina Service,
    The New York Eye and Ear Infirmary, New York, New York
  • J. M. Liebmann
    Ophthalmology,
    The New York Eye and Ear Infirmary, New York, New York
    Ophthalmology, New York University School of Medicine, New York, New York
  • R. Ritch
    Ophthalmology,
    The New York Eye and Ear Infirmary, New York, New York
    Ophthalmology, Einhorn Clinical Research Center, New York, New York
  • Footnotes
    Commercial Relationships  J.H. Kim, None; T.S. Prata, None; V.C. Lima, None; C.G.V. DeMoreas, None; S. Dorairaj, None; W. Seiple, None; R. Rosen, None; J.M. Liebmann, None; R. Ritch, None.
  • Footnotes
    Support  Joseph and Geraldine LaMotta Research Fund of the New York Glaucoma Research Institute, New York, NY
Investigative Ophthalmology & Visual Science April 2009, Vol.50, 2535. doi:
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      J. H. Kim, T. S. Prata, V. C. Lima, C. G. V. DeMoreas, S. Dorairaj, W. Seiple, R. Rosen, J. M. Liebmann, R. Ritch; A Comparison Between Microperimetry and Standard Achromatic Perimetry in Glaucomatous Patients With Central Scotomas. Invest. Ophthalmol. Vis. Sci. 2009;50(13):2535.

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Abstract

Purpose: : We evaluated retinal sensitivity using microperimetry in glaucomatous eyes with central visual field loss detected by achromatic standard automated perimetry (SAP), and correlated microperimetry with SAP results.

Methods: : We included 20 eyes of 14 patients with glaucomatous optic neuropathy and central (10°) visual field loss. Eyes with other diseases that could affect the central visual field were excluded. All patients underwent microperimetry (Opko/OTI, Toronto, Canada; Humphrey 10-2 pattern) and SAP (SITA-Standard 10-2) within 2 months. Results for each eye were divided into 4 quadrants for analysis. Linear regression was used to correlate the mean values of microperimetry thresholds (dB) and SAP thresholds (dB) in each quadrant. Normal and abnormal quadrants by SAP were compared to the corresponding quadrants using microperimetry, and macular thickness data (Stratus OCT) was used in cases of disagreement.

Results: : Mean age and MD were 60.8±13.4 years and -7.3±6.1 dB, respectively. There was a strong correlation between microperimetry and SAP results in all quadrants (inferior temporal quadrant, r2=0.85; IN, r2=0.72; SN, r2=0.65; ST, r2=0.64; p<0.01). All abnormal SAP quadrants (depression of at least 10 dB at one point or of 5 dB in ≥ 2 contiguous points) had a corresponding abnormal microperimetry quadrant (depression of at least 10 dB in one point or of 8 dB in ≥2 contiguous points). However, 21% (8/38) of the normal SAP quadrants had an abnormal corresponding microperimetry result (6 eyes); a corresponding OCT abnormality was present in 72% of these quadrants.

Conclusions: : Retinal sensitivity evaluated by microperimetry correlated strongly with SAP results in glaucomatous patients with central scotomas. Microperimetry detected retinal sensitivity reduction in areas of structural damage with normal SAP and suggests that microperimetry can be used as a more sensitive tool to detect visual function loss in glaucomatous eyes.

Keywords: visual fields • perimetry • retina 
© 2009, The Association for Research in Vision and Ophthalmology, Inc., all rights reserved. Permission to republish any abstract or part of an abstract in any form must be obtained in writing from the ARVO Office prior to publication.
Copyright © 2025 Association for Research in Vision and Ophthalmology.
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