April 2009
Volume 50, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2009
Reclassification of Normal- and High-Tension Glaucoma Eyes Using Corneal Compensated Intraocular Pressure
Author Affiliations & Notes
  • T. Paul
    Ophthalmology, Weill Med College Cornell Univ, New York, New York
  • N. M. Radcliffe
    Ophthalmology, Weill Med College Cornell Univ, New York, New York
  • M. Shimmyo
    Ophthalmology, New York Medical College; New York Eye and Ear Infirmary, New York, New York
  • Footnotes
    Commercial Relationships  T. Paul, None; N.M. Radcliffe, None; M. Shimmyo, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science April 2009, Vol.50, 2849. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      T. Paul, N. M. Radcliffe, M. Shimmyo; Reclassification of Normal- and High-Tension Glaucoma Eyes Using Corneal Compensated Intraocular Pressure. Invest. Ophthalmol. Vis. Sci. 2009;50(13):2849.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose: : The accuracy of Goldmann applanation tonometry (GAT) in measuring intraocular pressure (IOP) is affected by material properties of the cornea. We measured IOP by GAT and corneal compensated IOP (IOPcc) using Reichert's Ocular Response Analyzer (ORA) to evaluate whether use of IOPcc would affect the classification of eyes into normal- and high-tension categories.

Methods: : Cross-sectional observational review. IOP measurements of 1875 consecutive patients in a general ophthalmology practice were reviewed. Corneal hysteresis (CH), corneal resistance factor (CRF) and central corneal thickness (CCT) of randomly selected one eye of 357 normal, 155 high tension glaucoma (HTG) and 102 normal tension glaucoma (NTG) were compared. Eyes were classified as normal or glaucomatous based on the absence or presence of glaucomatous optic neuropathy (GON). The highest GAT recorded in a patient in an untreated state was used to divide patients into HTG (>21 mmHg) and NTG (< or = to 21mmHg) categories.

Results: : The mean IOPcc and GAT were similar in normal eyes and HTG eyes. In NTG eyes, the mean IOPcc of 19.8 mmHg was considerably higher than the mean GAT of 14.4 mmHg. In addition, NTG eyes had significantly thinner mean CCT of 513 µm, a lower CH of 5.96 mmHg, and a lower CRF of 6.31 mmHg (p<0.001) when compared to normal eyes which had a mean CCT of 541 µm, CH of 10.6 mmHg, and CRF of 10.15 mmHg. Many eyes (72%) considered to have NTG by traditional GAT threshold of 21mmHg were reclassified as HTG by IOPcc threshold of 18mmHg.

Conclusions: : In NTG eyes, corneal compensated IOP measurements reveal a higher IOP than traditional GAT measurements.

Keywords: intraocular pressure • anterior segment • anatomy 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×