April 2009
Volume 50, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2009
Application of Adaptive Optics - Optical Coherence Tomography for Imaging Eyes With Idiopathic Epiretinal Membrane
Author Affiliations & Notes
  • S. Pilli
    Ophthalmology, University of California, Davis, Sacramento, California
  • R. J. Zawadzki
    Ophthalmology, University of California, Davis, Sacramento, California
  • J. W. Evans
    Ophthalmology, University of California, Davis, Sacramento, California
  • S. S. Park
    Ophthalmology, University of California, Davis, Sacramento, California
  • J. S. Werner
    Ophthalmology, University of California, Davis, Sacramento, California
  • Footnotes
    Commercial Relationships  S. Pilli, None; R.J. Zawadzki, None; J.W. Evans, None; S.S. Park, None; J.S. Werner, None.
  • Footnotes
    Support  National Eye Institute (EY 014743) and RPB
Investigative Ophthalmology & Visual Science April 2009, Vol.50, 3299. doi:
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      S. Pilli, R. J. Zawadzki, J. W. Evans, S. S. Park, J. S. Werner; Application of Adaptive Optics - Optical Coherence Tomography for Imaging Eyes With Idiopathic Epiretinal Membrane. Invest. Ophthalmol. Vis. Sci. 2009;50(13):3299.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To evaluate the feasibility of adaptive optics - optical coherence tomography (AO-OCT) in delineating the microscopic retinal morphological changes at the fovea and perifoveal area in eyes with idiopathic epiretinal membrane (ERM).

Methods: : An AO-OCT retinal imaging system developed at our institution was employed for imaging retinae with idiopathic epiretinal membrane confirmed both clinically and on high-resolution FD-OCT. The AO-OCT system used in this study offers isotropic axial and lateral resolution of 3.5 µm for detailed in-vivo retinal imaging. We imaged 8 eyes of 5 patients, with visual acuity ranging from 20/20 to 20/40.

Results: : Microscopic changes in retinal morphology associated with idiopathic epiretinal membrane could be visualized using our AO-OCT retinal imaging system. As illustrated below from one of the eyes with ERM leading to lamellar hole formation, AO-OCT imaging resulted in improved visualization of splitting in the outer plexiform layer and the integrity of the photoreceptor inner and outer segment junction.

Conclusions: : AO -OCT is a novel imaging technique with increased axial and lateral resolution permitting improved visualization of the retinal layers and the associated morphologic changes.

Keywords: imaging/image analysis: clinical • retina 
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