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J. W. Kitchens, T. Stone, S. Westhouse, D. Sommerville, R. Isernhagen, W. Wood; Ultra-Widefield Fluorescein Angiography Prompted and Guided Treatment for Uveitis. Invest. Ophthalmol. Vis. Sci. 2009;50(13):3314.
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To determine the utility of ultra-widefield fluorescein angiography in prompting and guiding treatment of patients with uveitis.
A retrospective analysis was performed on 8 patients with uveitis who had undergone imaging with ultra-widefield angiography (Optos plc, Dunfernline, Scotland, UK). The analysis was to determine if diagnostic or treatment management decisions were enhanced by the widefield dynamic images.
Of the 8 patients with uveitis imaged with the Optomap P200MA, a treatment decision was made or altered based on the findings of the ultra-wide angle angiogram in 4 cases (50%). One patient with intermediate uvieits (IU) secondary to sarcoidosis recieved additional immunomodulatory therapy due to peripheral vascular leakage visualized on ultra-wide angle angiography. A second patient with idiopathic IU was started on immunomodulatory therapy due to the severity of peripheral vascular leakage in the affected eye and the presence of more extensive involvment in the fellow eye. The third and fourth patients had multifocal choroiditis (MFC) and serpiginous choroiditis. These patients underwent additional steroid therapy due to the presence of active lesions visualized outside of the macular area by the ultra-widefield angiogram.
Ultra-widefield angiography ia a useful adjunct in the diagnosis and treatment of uveitis. Dynamic widefield imaging can allow for patients with uveitis to be treated more effectively than previously indicated due to its ability to image the peripheral retina. In addition, the ability to capture simultaneous widefield images diminishes the possibility of missing active lesions outside the macular area.
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