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N. Horgan, C. L. Shields, A. Mashayekhi, J. A. Shields; A Pilot Study Comparing the Efficacy of Intravitreal Bevacizumab Versus Intravitreal Triamcinolone in the Treatment of Macular Edema Following Plaque Radiotherapy for Uveal Melanoma. Invest. Ophthalmol. Vis. Sci. 2009;50(13):3383.
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uTo compare the short-term efficacy of intravitreal bevacizumab versus intravitreal triamcinolone in the treatment of macular edema following plaque radiotherapy for uveal melanoma.
A comparative interventional series of 25 cases.
At 3-months follow-up mean reduction in central foveal thickness was 182 µm in the triamcinolone group compared to 49 µm in the bevacizumab group. Vision gain of one line or more was achieved in 61% of the triamcinolone group compared to 14% of the bevacizumab group.
Intravitreal triamcinolone may be more effective than intravitreal bevacizumab in the treatment of macular edema following plaque radiotherapy of uveal melanoma. A larger controlled study is warranted.
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