April 2009
Volume 50, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2009
Autofluorescence of Choroidal Hemangioma in 34 Consecutive Eyes
Author Affiliations & Notes
  • A. Ramasubramanian
    Ocular Oncology, Wills Eye Institute, Philadelphia, Pennsylvania
  • C. L. Shields
    Ocular Oncology, Wills Eye Institute, Philadelphia, Pennsylvania
  • S. A. Harmon
    Ocular Oncology, Wills Eye Institute, Philadelphia, Pennsylvania
  • J. A. Shields
    Ocular Oncology, Wills Eye Institute, Philadelphia, Pennsylvania
  • Footnotes
    Commercial Relationships  A. Ramasubramanian, None; C.L. Shields, None; S.A. Harmon, None; J.A. Shields, None.
  • Footnotes
    Support  Support provided by the Mellon Charitable Giving from the Martha W.Rogers Charitable Trust, Philadelphia, Pennsylvania (AR,CLS), Retina Research Foundation (Charles L. Schepens Lecture) of the Retina
Investigative Ophthalmology & Visual Science April 2009, Vol.50, 3687. doi:
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    • Get Citation

      A. Ramasubramanian, C. L. Shields, S. A. Harmon, J. A. Shields; Autofluorescence of Choroidal Hemangioma in 34 Consecutive Eyes. Invest. Ophthalmol. Vis. Sci. 2009;50(13):3687.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To describe the autofluorescence features of choroidal hemangioma

Methods: : Standard fundus photography and autofluorescence (AF) photography (580 nm excitation, 695 nm barrier filter) were performed on all patients. Clinical features were correlated with autofluorescence features.

Results: : There were 27 eyes with circumscribed choroidal hemangioma (CCH) and 7 eyes with diffuse choroidal hemangioma (DCH). The mean patient age was 53 years for CCH and 15 years for DCH. Intrinsic AF of untreated CCH was generally isoAF (n=7, 58%) and for treated CCH was hypoAF (n=15, 100%). Extrinsic AF of CCH disclosed hyperAF (orange pigment and fresh subretinal fluid) and hypoAF (RPE hyperplasia, fibrous metaplasia, and atrophy). Intrinsic AF of untreated DCH was generally hypoAF (n=2, 67%) and for treated DCH was hypoAF (n=3, 75%). Extrinsic AF of DCH was similar to CCH.

Conclusions: : Choroidal hemangioma shows little intrinsic autofluorescence. Overlying orange pigment and fresh subretinal fluid show hyperAF and RPE hyperplasia and atrophy show hypoAF.

Keywords: oncology • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • imaging/image analysis: clinical 
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