April 2009
Volume 50, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2009
Evaluation of Optic Nerve Head Drusen Using Spectral-domain OCT (Spectralis)
Author Affiliations & Notes
  • L. Storm
    Ophthalmology, University of Florida, Jacksonville, Florida
  • R. Keshavamurthy
    Ophthalmology, University of Florida, Jacksonville, Florida
  • V. Brar
    Ophthalmology, University of Florida, Jacksonville, Florida
  • K. V. Chalam
    Ophthalmology, University of Florida, Jacksonville, Florida
  • S. Grover
    Ophthalmology, University of Florida, Jacksonville, Florida
  • Footnotes
    Commercial Relationships  L. Storm, None; R. Keshavamurthy, None; V. Brar, None; K.V. Chalam, None; S. Grover, None.
  • Footnotes
    Support  Foundation Fighting Blindness, Inc., Owings Mills, Maryland.
Investigative Ophthalmology & Visual Science April 2009, Vol.50, 4022. doi:
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    • Get Citation

      L. Storm, R. Keshavamurthy, V. Brar, K. V. Chalam, S. Grover; Evaluation of Optic Nerve Head Drusen Using Spectral-domain OCT (Spectralis). Invest. Ophthalmol. Vis. Sci. 2009;50(13):4022.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : Optic nerve head drusen (ONHD) are white calcareous deposits, seen either superficially on the optic nerve head or buried within it. Diagnosis of ONHD is made by one or more ways: clinical exam, autofluorescence, ultrasound of the optic nerve, CT scan and/or visual field examination. The present study describes features of ONHD based on another diagnostic modality, the spectral-domain OCT (Spectralis).

Methods: : This is an observational case series of 5 patients with bilateral ONHD with a best-corrected visual acuity of 20/20 and no other posterior segment pathology. All the patients underwent fundus photography, fundus autofluorescence, B-scan ultrasonography, Spectralis OCT and Humphrey 30-2 threshold visual fields.

Results: : All 5 patients had surface ONHD which were autofluorescent and echodense on B-scan ultrasonography. Spectralis OCT findings in the corresponding areas include 'scattered spots with high reflectivity' casting a shadow underneath. The reflectivity can be distinctly differentiated from the blood vessels on the optic nerve. Two thirds of the patients had an arcuate scotoma on the Humphrey visual fields. No correlation was found between the changes on Spectralis OCT with that of visual field.

Conclusions: : Spectralis OCT is another useful ancillary investigation in the diagnosis of ONHD and we describe the features in the present study.

Keywords: optic nerve • drusen • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) 
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