April 2009
Volume 50, Issue 13
ARVO Annual Meeting Abstract  |   April 2009
Prevalence of Alcohol Consumption and Risk of Ocular Diseases in a General Population: The Beijing Eye Study
Author Affiliations & Notes
  • Q. You
    Physiology, Beijing Inst of Ophthalmology, Beijing, China
  • L. Xu
    Physiology, Beijing Inst of Ophthalmology, Beijing, China
  • J. B. Jonas
    Physiology, Beijing Inst of Ophthalmology, Beijing, China
    Department of Ophthalmology, Medical Faculty Mannheim of he Ruprecht-Karls-University of Heidelberg, Mannheim, Germany
  • Footnotes
    Commercial Relationships  Q. You, None; L. Xu, None; J.B. Jonas, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science April 2009, Vol.50, 4093. doi:
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      Q. You, L. Xu, J. B. Jonas; Prevalence of Alcohol Consumption and Risk of Ocular Diseases in a General Population: The Beijing Eye Study. Invest. Ophthalmol. Vis. Sci. 2009;50(13):4093.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose: : To examine the associations between alcohol consumption and ocular diseases in the adult population of mainland China.

Methods: : The Beijing Eye Study was a population based eye study, performed in 2001, included 4439 subjects (age 40+ years) out of 5324 subjects invited to participate (response rate 83.4%). It was held in a rural region (1973 subjects) and an urban region of Greater Beijing (2466 subjects). The participants underwent an interview including questions for alcohol consumption and a detailed ophthalmic examination including photography of the cornea, lens and fundus.

Results: : Information on alcohol consumption was obtained for 4141 (93.3%) subjects, out of whom 549 (13.3%) subjects reported to consume beer or wine. In multivariate analysis, alcohol consumption was significantly associated with the systemic parameters of lower age (P=0.001), male gender (P<0.001), rural region (P<0.001), lower level of education (P=0.01), and smokers/nonsmokers (P<0.001). Alcohol consumption was not significantly associated with the prevalences of age-related macular degeneration (P=0.24), open-angle glaucoma (P=0.51), angle-closure glaucoma (P=075), diabetic retinopathy (P=0.35), retinal vein occlusions (P=0.39), pterygia (P=0.08), trachoma (P=0.053), epiretinal membranes (P=0.09), non-glaucomatous optic nerve atrophy (P=0.55), dry eye (P=0.86), cortical cataract (P=0.67), subcapsular posterior cataract (P=0.62), and nuclear cataract (P=0.76) nor with the ocular parameters of refractive error (P=0.99), intraocular pressure (P=0.19), retinal artery diameters (temporal inferior: P=0.60), retinal vein diameters (temporal inferior: P=0.41), and size of alpha zone and beta zone of parapapillary atrophy (P=0.68).

Conclusions: : When adjusted for the systemic parameters of age, gender, rural / urban region, level of education and smoking, a moderate consumption of alcohol as reported by the subjects may not have a major effect on the prevalence of the major ocular diseases such as age-related macular degeneration, open-angle glaucoma and angle-closure glaucoma, diabetic retinopathy, retinal vein occlusions, epiretinal membranes, trachoma, pterygium and dry eye, nor on the physiologic parameters of intraocular pressure and refractive error.

Keywords: age-related macular degeneration • cataract • intraocular pressure 

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