Abstract
Purpose: :
To evaluate the implementation of a new symptom questionnaire (OSDI modified into Japanese) into the revised Japan Dry Eye Diagnostic Criteria and to investigate the changes in the dry eye diagnosis.
Methods: :
239 Subjects (75 males, 164 females, average age 39.7 years) who were seen for general and dry eye examination, filled out a questionnaire (modified OSDI) with questions pertaining to alternations in visual function, ocular symptoms, and environmental triggers often associated with dry eye disease. A dry eye severity score (DESS) was given based on the numbers of questions and the total scores. From the results of Schirmer I test (ST), tear break up time (BUT), and fluorescein (F) and Rose Bengal (RB) staining, patients were diagnosed with Definite Dry Eye (DDE), Probable Dry Eye (PDE), or Not Dry Eye (nonDE), using both the old and revised diagnostic criteria.
Results: :
All 44 subjects diagnosed as non DE under the old criteria were diagnosed as nonDE under the new diagnostic criteria. Fifty seven subjects diagnosed as PDE under the old criteria were diagnosed as nonDE (18 subjects) and PDE (39 subjects) in new diagnostic criteria. Under the old criteria, 138 were diagnosed as DDE, however, under the new criteria 58 subjects were diagnosed as PDE and the remains 80 were diagnosed as DDE.The average DESS score under the new diagnostic criteria was 29.8 in nonDE, 33.2 in PDE, and 41.2 in DDE.
Conclusions: :
The DESS obtained from new symptom questionnaire was found to correspond well to the revised dry eye diagnosis. The new diagnosis criteria is expected to separate the severe dry eye patients from the moderate dry eye patients.
Keywords: clinical (human) or epidemiologic studies: risk factor assessment • cornea: tears/tear film/dry eye • lacrimal gland