April 2009
Volume 50, Issue 13
ARVO Annual Meeting Abstract  |   April 2009
Development of a National Prophylactic Program Against Neonatal Conjunctivitis in Angola: Pilot Study
Author Affiliations & Notes
  • J. C. Pastor
    IOBA (Eye Institute), University of Valladolid, Valladolid, Spain
  • I. R. D. C. Alexandre
    MINSA, IONA (Eye Institute), Luanda, Angola
  • Footnotes
    Commercial Relationships  J.C. Pastor, None; I.R.D.C. Alexandre, None.
  • Footnotes
    Support  Agencia Española de Cooperación Internacional y Desarrollo and Ministerio de Saúde de Angola
Investigative Ophthalmology & Visual Science April 2009, Vol.50, 5056. doi:
  • Views
  • Share
  • Tools
    • Alerts
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      J. C. Pastor, I. R. D. C. Alexandre; Development of a National Prophylactic Program Against Neonatal Conjunctivitis in Angola: Pilot Study. Invest. Ophthalmol. Vis. Sci. 2009;50(13):5056.

      Download citation file:

      © ARVO (1962-2015); The Authors (2016-present)

  • Supplements

Purpose: : After 30 years of civil war, Angola’s Health System has serious deficiencies. Angola created in 1990 an Eye Institute (IONA) which receives academic and technical support from the Eye Institute (IOBA) of the University of Valladolid, Spain since 1995. A large number of newborns with neonatal conjunctivitis (NC) are continuously attended at the IONA and there are not prophylactic measures for NC at the Angola's maternities. Thus, we developed this pilot study to analyze the prevalence of NC in the largest maternity of Luanda as a previous step to develop a National program to adopt NC prophylaxis, a project supported by the Spanish Agency for International Cooperation and Development (AECID)

Methods: : After Ethical Committee approval, a transversal study at the Augusto N’Gangula maternity between July and August 2006 was performed. 194 consecutive new-borns were included . Children were explored by two medical students and one ophthalmologist, with a light-pen, direct ophthalmoscope and indirect ophthalmoscope under mydriasis. Pathologic and doubtful cases were refered to the IONA for a complete ocular examination

Results: : 44 (22,6%) children showed ocular alterations: 24 (10,3%) showed bilateral NC; 20 eyes showed retinal haemorrhages, 8 eyes conjunctival haemorrhages, one child had bilateral glaucoma and one albinism. 74% (143) of the mothers had an appropriate follow up during pregnancy; 15% (29) had poor control and 11,3% (22) had none. 36 mothers have previous history of urinary infection, 16 vulvo-vaginitis, 2 had AIDS and 1 had syphilis.132 labours were by caesarean and 62 via vaginal. 20 (50%) children with NC were born by caesarean. Only 4 mothers of children with NC referred leukorrea. No microbiological identification was available at the maternity or at the IONA for this study

Conclusions: : Incidence of NC in Angola is ten times higher than in USA or Europe (1-2%) so prophylaxis must be started. A microbiologic identification is required and it is important to develop a prospective, randomized case-control study using 5% povidone-iodine eye-drops to demonstrate to Angola’s authorities the efficacy of this prophylaxis to reduce this potential cause of neonatal blindness

Keywords: conjunctivitis • clinical (human) or epidemiologic studies: treatment/prevention assessment/controlled clinical trials • clinical (human) or epidemiologic studies: health care delivery/economics/manpower 

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.