April 2009
Volume 50, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2009
Structure-function Relationships With a Disc-centred Visual Field Test Grid
Author Affiliations & Notes
  • R. Asaoka
    NIHR Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, United Kingdom
    Ophthalmology, Hamamatsu University, School of Medicine, Hamamatsu, Shizuoka, Japan
  • E. White
    NIHR Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, United Kingdom
  • F. Amalfitano
    NIHR Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, United Kingdom
  • R. Malik
    NIHR Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, United Kingdom
  • H. Zhu
    NIHR Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, United Kingdom
    Department of Optometry and Visual Science, City University London, London, United Kingdom
  • D. Garway-Heath
    NIHR Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, United Kingdom
    Department of Optometry and Visual Science, City University London, London, United Kingdom
  • Footnotes
    Commercial Relationships  R. Asaoka, None; E. White, None; F. Amalfitano, None; R. Malik, None; H. Zhu, None; D. Garway-Heath, None.
  • Footnotes
    Support  Scientist exchange program of the Japan Society for the Promotion of Science
Investigative Ophthalmology & Visual Science April 2009, Vol.50, 4400. doi:
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      R. Asaoka, E. White, F. Amalfitano, R. Malik, H. Zhu, D. Garway-Heath; Structure-function Relationships With a Disc-centred Visual Field Test Grid. Invest. Ophthalmol. Vis. Sci. 2009;50(13):4400.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To compare the retinal nerve fibre layer thickness (RNFLT)/visual field (VF) structure/function relationship with a newly created disc-centred visual field (DCF) and the fovea-centred standard automated perimetry (SAP).

Methods: : 50 eyes with ocular hypertension or open angle glaucoma were enrolled (average MD -9.4 ± 7.0dB, range +1.6 to -25.6dB). SAP was measured with the Humphrey 24-2 (full threshold). DCF was created using the Humphrey Field Analyzer (full threshold) (Figure 1). RNFLT was measured with Stratus optical coherence tomography (OCT). Linear regression between VF log (sector mean sensitivity in linear units) and log RNFLT was performed for each sector and for the whole VF. Residuals of linear regression fits were compared by paired t-tests.

Results: : The number of test points and R2 structure/function association values for each sector are shown in Table 1.

Keywords: visual fields • imaging/image analysis: clinical • optic disc 
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