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A. Bayer, A. ahin, O. Dal; Comparison of Optic Nerve Head Topography, Visual Field Patterns, and Visual Field Indices in Primary Open-angle and Exfoliation Glaucoma. Invest. Ophthalmol. Vis. Sci. 2009;50(13):4409.
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To compare the optic nerve head topography, visual field (VF) patterns, and VF indices in eyes with primary open-angle glaucoma (POAG) and exfoliation glaucoma (PEXG).
A total of 311 patients, 289 with POAG and 42 with PEXG were enrolled in this study. Each study participant underwent detailed ophthalmologic examination, central corneal pachymetry, standard automated perimetry, and Heidelberg Retinal Tomograph (HRT-III) optic nerve head evaluation. Visual field patterns were classified as superior and inferior nasal step, borderline, superior and inferior hemifield defects, superior and inferior arcuate defects, generalized depression, and paracentral scotomas. Included visual field indices were mean deviation (MD) and pattern standard deviation (PSD). Visual field pattern distributions were compared by using chi-square test. Optic nerve head topographic parameters and visual field indices were compared by using independent sample t-test. p<0.05 was considered as statistically significant.
Mean age of the patients with POAG and PEXG were 59.1±16 years and 67.8±10 years, respectively. The VF average MD and PSD did not significantly differ between POAG and PEXG (p>0.05). Among HRT parameters, height variation contour, mean RNFL thickness, RNFL cross sectional area, CLM temporal-superior, and average variability differed significantly between POAG and PEXG (p<0.05). Moorfields classification of HRT revealed significant differences between POAG and PEXG patients (p<0.05). The VF patterns were also differed between POAG and PEXG (p<0.05).
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