April 2009
Volume 50, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2009
Blood Pressure and the Risk of Incident Diabetic Retinopathy in a Latino Population: The Los Angeles Latino Eye Study (LALES)
M. Javaheri; J. Chung; M. Torres; S. Azen; R. Klein; R. Varma; the LALES group
Author Affiliations & Notes
  • M. Javaheri
    Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, California
  • J. Chung
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California
  • M. Torres
    Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, California
  • S. Azen
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California
  • R. Klein
    Ophthalmology, University of Wisconsin, Madison, Wisconsin
  • R. Varma
    Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, California
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California
  • the LALES group
    Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, California
  • Footnotes
    Commercial Relationships  M. Javaheri, None; J. Chung, None; M. Torres, None; S. Azen, None; R. Klein, None; R. Varma, None.
  • Footnotes
    Support  EY-11753, EY-03040
Investigative Ophthalmology & Visual Science April 2009, Vol.50, 4417. doi:
  • Views
  • Share
  • Tools
    • Alerts
      User Alerts
      You are adding an alert for:
      Blood Pressure and the Risk of Incident Diabetic Retinopathy in a Latino Population: The Los Angeles Latino Eye Study (LALES)
      You will receive an email whenever this article is corrected, updated, or cited in the literature. You can manage this and all other alerts in My Account
      The alert will be sent to:
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation
      Citation

      M. Javaheri, J. Chung, M. Torres, S. Azen, R. Klein, R. Varma, the LALES group; Blood Pressure and the Risk of Incident Diabetic Retinopathy in a Latino Population: The Los Angeles Latino Eye Study (LALES). Invest. Ophthalmol. Vis. Sci. 2009;50(13):4417.

      Download citation file:

      © ARVO (1962-2015); The Authors (2016-present)

      ×
    • Get Permissions
  • Supplements
Abstract

Purpose: : To determine the association between blood pressure and the four-year incidence of diabetic retinopathy (DR) in a population-based sample of Latinos with type 2 diabetes mellitus (T2DM).

Methods: : The data for this analysis is derived from the Los Angeles Latino Eye Study (LALES), a population-based prevalence study of eye disease in Latinos (primarily Mexican-Americans) age 40 and older. Eight hundred ninety three participants underwent a comprehensive examination including measurement of systolic and diastolic blood pressure, glycosylated hemoglobin, stereoscopic fundus photographs ( 7 standard Early Treatment Diabetic Retinopathy Study fields) in addition to completing a standard in-home interview at baseline and a 4 year follow-up visit. Photographs were graded in a masked manner using a Modified Arlie House classification system to assess presence and severity of DR. Persons with a diagnosis of definite T2DM and no evidence of retinopathy at the baseline examination were included in this analysis. Univariate and multivariate analyses were used to identify if there was an independent relationship between blood pressure and the 4-year risk of developing DR.

Results: : Of the 1082 persons with diabetes mellitus a baseline, 544 had DR at baseline. Thus, 412 persons with T2DM were included in this analysis. The mean systolic and diastolic blood pressure in persons with DR was 127mmHg and 76mmHg. The mean systolic and diastolic blood pressure in persons without DR was 128mmHg and 76mmHg. These differences were not statistically significant (per 10mmHg systolic, OR=1.031 (0.905, 1.174), per 10mmHg diastolic, OR= 0.963 (0.769, 1.206), p≥0.44). Furthermore, in the multivariate model, after adjusting for age, glycosylated hemoglobin level, random blood glucose level, and body mass index, these differences were not significant.

Conclusions: : Systolic and Diastolic blood pressures are not associated with a higher incidence of DR in our Latino population. While blood pressure control is important, it does not appear to play a significant role in the development of retinopathy in Latinos.

Keywords: clinical (human) or epidemiologic studies: risk factor assessment • clinical (human) or epidemiologic studies: prevalence/incidence • diabetic retinopathy 
© 2009, The Association for Research in Vision and Ophthalmology, Inc., all rights reserved. Permission to republish any abstract or part of an abstract in any form must be obtained in writing from the ARVO Office prior to publication.
Copyright © 2025 Association for Research in Vision and Ophthalmology.
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×
This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy.Accept