Abstract
Purpose: :
To know the epidemiological characteristics and possible associated factors of anterior uveitis related to diabetes mellitus in a mexican mestizo population.
Methods: :
The study was divided in two phases: in the first phase all the files from patients admitted to the service of ocular inflammatory diseases from november 2007 to july 2008 under the diagnosis of anterior uveitis related to diabetes mellitus were reviewed. The following variables were captured: sex, age, type of diabetes, treatment, time of diagnosis, presence or not of diabetic retinopathy and glucemic levels. In the second phase, diabetic patients without prior surgery or panretinal photocoagulation who came to consult for the first time, regardless of the reason for consultation, were randomly selected and the same variables were captured as well submitted to an intentional search for inflammatory signs in the anterior chamber, from september 1st 2008 to december 1st 2008.
Results: :
First phase: Information of 28 eyes (26 patients, 12 male and 14 female) was gathered. Mean age was at the time of diagnosis was of 56.28 years, with an mean interval of 12.66 years between the diagnosis of diabetes and the one of uveitis. Mean glucemic levels were 229.54 mg/dL, mean glycosylated hemoglobin percentage was 13.33%, Glybenclamide and Insulin were the prevalent type of treatment and 50% of the patients didn’t have diabetic retinopathy at the time of diagnosis. Second phase: there were 67 patients (29 women and 37 men) , with a mean age of 59.31 years, age of diagnosis 48.49 years and a mean interval between diagnosis of 10.81 years. Mean glucemic levels were 154.87 mg/dL, glybenclamide was the preferred treatment and 52.2% of the patients didn’t have diabetic retinopathy. Only one patient presented anterior uveitis.
Conclusions: :
Patients without diabetic retinopathy are more likely to develop anterior uveitis and is more frequent in patients treated with insulin and glybenclamide.The time of evolution of diabetes in the patient is not related in a direct way with the presence or not of anterior uveitis.
Keywords: uvea • diabetes • anterior segment