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G. kaswin, R. Legras, I. De Monchy, G. Gendron, H. Offret, M. Labetoulle; Wavefront Analysis in Unilateral Herpetic Keratisis. Invest. Ophthalmol. Vis. Sci. 2009;50(13):5126.
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The assess optical aberrations using wavefront analysis in the affected eye of patients with unilateral herpetic keratitis with no apparent visual disturbance (visual acuity : 20/20), and to compare these results with those of the non-affected eye.
Zernike’s polynoms and MTF curve analysis showed bilateral abnormalities in 4 patients, with no significant difference between the two eyes. In contrast, one patient had significant wavefront disturbances in the affected eye, whereas the non-affected eye was normal.
Moderate herpetic keratisis may induce wavefront abnormalities in some patients despite a normal visual acuity and an apparently normal cornea. This could explain visual discomfort that is sometimes described in such patients. A prospective study including more patients should give more information on the rate and clinical significance of these optical aberrations.
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