April 2009
Volume 50, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2009
Combined Hamartoma of the Retina and Retinal Pigment Epithelium in 77 Consecutive Patients
Author Affiliations & Notes
  • A. Thangappan
    Oncology, Wills Eye Institute, Philadelphia, Pennsylvania
  • K. Hartzell MD
    Oncology, Wills Eye Institute, Philadelphia, Pennsylvania
  • C. L. Shields MD
    Oncology, Wills Eye Institute, Philadelphia, Pennsylvania
  • P. Valente MD
    Oncology, Wills Eye Institute, Philadelphia, Pennsylvania
  • C. Pirondini MD
    Oncology, Wills Eye Institute, Philadelphia, Pennsylvania
  • J. A. Shields MD
    Oncology, Wills Eye Institute, Philadelphia, Pennsylvania
  • Footnotes
    Commercial Relationships  A. Thangappan, None; K. Hartzell MD, None; C.L. Shields MD, None; P. Valente MD, None; C. Pirondini MD, None; J.A. Shields MD, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science April 2009, Vol.50, 5230. doi:
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    • Get Citation

      A. Thangappan, K. Hartzell MD, C. L. Shields MD, P. Valente MD, C. Pirondini MD, J. A. Shields MD; Combined Hamartoma of the Retina and Retinal Pigment Epithelium in 77 Consecutive Patients. Invest. Ophthalmol. Vis. Sci. 2009;50(13):5230.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To evaluate clinical characteristics and visual outcomes.

Methods: : Retrospective review.

Results: : Of 77 patients, the mean age at presentation was 12 years. The majority were Caucasian(91%) and male(68%). Referring diagnosis was correct in 25% of cases. Incorrect diagnoses included melanoma (8%), nevus (6%), and retinoblastoma (5%). The most common presenting symptom was decreased visual acuity (32%). The mean tumor thickness was 2mm and base 8mm. The visual acuity decreased from initial visit (macular tumor 20/320, extramacular tumor 20/80) to 10-year follow-up (macular tumor 20/2000, extramacular tumor 20/100).

Conclusions: : Combined hamartoma is often misdiagnosed. Progressive visual loss is common, particularly with macular tumors.

Keywords: retina • retinal pigment epithelium • tumors 
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