April 2009
Volume 50, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2009
A Case of Bilateral Diffuse Uveal Melanocytic Proliferation With a Positive Response to Plasmapheresis
Author Affiliations & Notes
  • R. B. Mets
    Ophthalmology, Northwestern Univ Feinberg Sch of Med, Chicago, Illinois
  • L. M. Jampol
    Ophthalmology, Northwestern Univ Feinberg Sch of Med, Chicago, Illinois
  • Footnotes
    Commercial Relationships  R.B. Mets, None; L.M. Jampol, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science April 2009, Vol.50, 5243. doi:
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    • Get Citation

      R. B. Mets, L. M. Jampol; A Case of Bilateral Diffuse Uveal Melanocytic Proliferation With a Positive Response to Plasmapheresis. Invest. Ophthalmol. Vis. Sci. 2009;50(13):5243.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : to present a case of Bilteral diffuse melanocytic proliferation associated with metastatic renal cell carcinoma, with an excellent visual response to plasmapheresis.

Methods: : We studied the case of a 72 year old Caucasian male with a recent diagnosis of renal cell carcinoma, metastatic to his lung, and gradual onset of blurred vision in both eyes. Fundus findings were consistent with BDUMP. The patient was treated with plasmapheresis.

Results: : Both vision and fundus findings improved with plasmapheresis. There was loss of serous detachments, decrease in orange pigmentation, and increased visibility of underlying pigmented tumors.

Conclusions: : Plasmapheresis should be considered as a treatment methodology in patients with visual loss from bilateral diffuse melanocytic proliferation.

Keywords: retina • melanocytes • oncology 
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