Abstract
Purpose: :
To identify changes in retinal anatomy with Spectral Domain Optical Coherence Tomography (SD-OCT) before and after panretinal photocoagulation (PRP) treatment with pattern scan laser (PASCAL) in eyes of patients with proliferative diabetic retinopathy (PDR).
Methods: :
Eight eyes of patients with PDR were imaged using SD-OCT before and after PRP treatment with pattern scan laser. Images were registered and then compared.
Results: :
SD-OCT images illustrated acute morphological changes after PRP that included focal destruction of the retinal pigment epithelium and photoreceptor layer in the center of the photocoagulation burn and surrounding tissue reaction including pigment epithelial detachment. Retinal thickness increased in the photocoagulation burns secondary to intraretinal fluid or exudation. The intensity of these changes decreased with weaker photocoagulation burns in the pattern scan demonstrating difference among photocoagulation burns in the semi-automated patterns.
Conclusions: :
SD-OCT identifies morphological changes after PRP treatment and allows anatomical insight into treatment efficacy with pattern scan lasers.
Keywords: imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • diabetic retinopathy • retina