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J.-H. Jang, Y.-C. Kim, K.-S. Kim; The Effect of Intravitreal Triamcinolone Acetonide Injection According to Macular Edema Type in Branch Retinal Vein Occlusion. Invest. Ophthalmol. Vis. Sci. 2009;50(13):5402.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate the clinical effect of an intravitreal triamcinolone acetonide injection (IVTA) in branch retinal vein occlusion according to different morphologic patterns of macular edema.
Retrospective, observational case series. Thirty-four eyes of 34 patients, who had been diagnosed macular edema in branch retinal vein occlusion, were studied. Each patient was classified as one of three macular edema type using Optical coherence tomography (OCT): cystoid macular edema, sponge-like macular edema, serous macular detachment. 34 eyes with macular edema in branch retinal vein occlusion received 4mg of a single IVTA. Primary outcome measures were a change of central macular thickness and an improvement of best-corrected visual acuity.
Cystoid macular edema was seen by optical coherence tomography in 16 of 34 eyes. Both sponge-likes macular edema and serous macular detachment were 9 eyes. An improvement of visual acuity at 24 weeks after injection was +0.25, +0.18, +0.27 in cystoid macular edema, sponge-likes macular edema, and serous macular detachment type, respectively. Only sponge-like macular edema had not significantly improvement of visual acuity (p=0.064). Central macular thickness was significantly reduced all three types; -344.25um, -337.44um, -372.29um in cystoid macular edema, sponge-likes macular edema, and serous macular detachment type, respectively (p < 0.05).
IVTA is more effective in the cystoid macular edema and serous retinal detachment type than in the sponge-like macular edema type in branch retinal vein occlusion. Further clinical studies with longer follow-up are required to evaluate the long-term outcomes.
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