Purchase this article with an account.
D. Ng, A. J. Kanellopoulos; Laboratory Intra-stromally Delivered Collagen Cross-Linking (iCCL) in an Advanced Bullous Keratopathy (BK) Model. Invest. Ophthalmol. Vis. Sci. 2009;50(13):5466.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
Evaluate a novel staged iCCL.
In 10 eye bank corneas, 2 sequential femtosecond derived pockets were used for iCCL with UVA exposure at 15mW/cm2 for 7 minutes each.
After iCCL UVA/Sham exposure, the mean clarity was 3.25 + SD for group A and 3.50 + SD for group B, while the mean thickness was 580 + SD µm for group A and 710 + SD µm for group B.
Staged UVA crosslinking (15mW/cm2) with intrastromal riboflavin may be a safe (no cornea scarring) and effective (marked reduction of edema) alternative method for managing bullous keratopathy.
This PDF is available to Subscribers Only