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E.-K. Kim, T.-I. Kim, J. Hong, H. Cho, J. Chung; The Determination of Treatment Strategies of Granular Dystrophy Type II Using Fourier Domain Optical Coherence Tomography. Invest. Ophthalmol. Vis. Sci. 2009;50(13):5503.
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The main goal of treatment for the improvement of vision in granular corneal dystrophy type II (GCDII) is how exactly to remove corneal deposits with minimal surgical procedures. We analyzed the depth, location and pattern of corneal deposits by using FT-OCT before and after surgical procedure.
Five GCD II patients were analyzed with the FD-OCT, RTVue-100® (Optovue Inc, CA) for the location and pattern of deposit. Two GCD II homozygotes were evaluated for depth and thickness of the main deposits before PTK. The third had previously undergone LASIK and newly formed opacities surrounding the flap interface were visualized. The last two cases were evaluated for the depth of visually significant deposits to determine surgical methods: penetrating keratoplasty or deep lamellar keartoplasty.
The measurement of corneal deposits and opacities using RTVue-100 FT-OCT revealed the depth of deposits quite precisely. According to the depth of the main deposit, the surgical method for each patient was planned and performed. Visually significant opacities were properly removed by each surgical procedure.
FD-OCT showed accuracy and feasibility for analyzing the corneal condition of GCDII patients before the surgery, non-invasively.
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