April 2009
Volume 50, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2009
Repeatability of Fast Transient Visual Evoked Potentials in Normal Subjects
Author Affiliations & Notes
  • J. Patel
    Diopsys Inc, Pine Brook, New Jersey
  • C. Tello
    Einhorn Clinical Research Center, New York Eye and Ear Infirmary, New York, New York
  • P. H. Derr
    Diopsys Inc, Pine Brook, New Jersey
  • C. G. V. De Moraes
    Einhorn Clinical Research Center, New York Eye and Ear Infirmary, New York, New York
  • E. Kim
    Einhorn Clinical Research Center, New York Eye and Ear Infirmary, New York, New York
  • T. S. Prata
    Einhorn Clinical Research Center, New York Eye and Ear Infirmary, New York, New York
  • J. M. Liebmann
    Einhorn Clinical Research Center, New York Eye and Ear Infirmary, New York, New York
    NYU School of Medicine, New York, New York
  • R. Ritch
    Einhorn Clinical Research Center, New York Eye and Ear Infirmary, New York, New York
  • Footnotes
    Commercial Relationships  J. Patel, Diopsys, E; C. Tello, Diopsys, Inc., R; P.H. Derr, Diopsys, E; C.G.V. De Moraes, None; E. Kim, None; T.S. Prata, None; J.M. Liebmann, Diopsys, R; R. Ritch, Diopsys, R.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science April 2009, Vol.50, 5879. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      J. Patel, C. Tello, P. H. Derr, C. G. V. De Moraes, E. Kim, T. S. Prata, J. M. Liebmann, R. Ritch; Repeatability of Fast Transient Visual Evoked Potentials in Normal Subjects. Invest. Ophthalmol. Vis. Sci. 2009;50(13):5879.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose: : To evaluate the within-session repeatability of a new fast transient visual evoked potential (ftVEP) in normal individuals.

Methods: : We tested 30 normal subjects (20/20 visual acuity, normal 24-2 SITA Standard VF) with ftVEP. Test duration was 20 seconds/eye. Synchronized single-channel ftVEPs were recorded using a modified Diopsys Enfant System (Diopsys, Inc., Pine Brook, New Jersey, USA), which generated a time series of 240 data points per analysis window. Two patterns were used in the study: 85% and 10% Michelson contrast. Each eye was tested 10 times (5 with 10% and 5 with 85% contrast). The following information was identified from the filtered N75-P100-N135 complex: N75 amplitude, N75 latency, P100 amplitude, P100 latency, Delta P100-N75 amplitude, and Delta P100-N75 latency. The standard deviations for the five ftVEPs for each OS, OD and OU at each contrast level were calculated. The standard deviations for OS, OD and OU were grouped into two data sets based on contrast level.

Results: : Mean age was 27.3±5.2 yrs. The total number of tests was 900 [30 patients x 3 (OD, OS, OU) x 5 (re-tests) x 2 (10% and 85%)]. The mean P100 latency at 10% and 85% contrast were 114.7 (95% CI: 113.4-116.1) and 103.7 (102.5-104.9), respectively. The table summarizes the repeatability data. The N75-P100 amplitudes were 5.1 (4.5- 5.7) and 8.0 (6.8-9.3), respectively. The inter-eye correlation was significant for both delta amplitudes and P100 latencies at 85% (r2 = 0.87 and r2=0.53, p<0.01, respectively) and at 10% (r2 = 0.48 and r2=0.41, p<0.01, respectively).

Conclusions: : FtVEP technology showed good within-session repeatability and good inter-eye correlation.Table 1: Within session variability (standard deviation values) of ftVEP parameters

Keywords: photoreceptors: visual performance • detection 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×