April 2009
Volume 50, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2009
Fs-Lentotomy: Change in Accommodation Amplitude of in vitro Crystalline Lenses by Fs-Laser Pulses
S. Schumacher; M. Fromm; U. Oberheide; H. Hoffmann; G. Gerten; A. Wegener; H. Lubatschowski
Author Affiliations & Notes
  • S. Schumacher
    Biomedical Optics Department, Laser Zentrum Hannover eV, Hannover, Germany
  • M. Fromm
    Biomedical Optics Department, Laser Zentrum Hannover eV, Hannover, Germany
  • U. Oberheide
    Laserforum Köln, Cologne, Germany
  • H. Hoffmann
    Biomedical Optics Department, Laser Zentrum Hannover eV, Hannover, Germany
  • G. Gerten
    Laserforum Köln, Cologne, Germany
  • A. Wegener
    Department of Ophthalmology, University of Bonn, Bonn, Germany
  • H. Lubatschowski
    Biomedical Optics Department, Laser Zentrum Hannover eV, Hannover, Germany
  • Footnotes
    Commercial Relationships  S. Schumacher, None; M. Fromm, None; U. Oberheide, Uwe Oberheide, P; H. Hoffmann, None; G. Gerten, None; A. Wegener, None; H. Lubatschowski, Holger Lubatschowski, P.
  • Footnotes
    Support  Grant: BmbF FKZ 13N8709 & 13N8712
Investigative Ophthalmology & Visual Science April 2009, Vol.50, 6133. doi:
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      S. Schumacher, M. Fromm, U. Oberheide, H. Hoffmann, G. Gerten, A. Wegener, H. Lubatschowski; Fs-Lentotomy: Change in Accommodation Amplitude of in vitro Crystalline Lenses by Fs-Laser Pulses. Invest. Ophthalmol. Vis. Sci. 2009;50(13):6133.

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Abstract

Purpose: : The aim to treat presbyopia is a current field of research. One concept based on the Helmholtz theory of accommodation is the femtosecond-lentotomy. Femtosecond laser pulse induced micro incisions inside the crystalline lens create gliding planes which increase the flexibility of the hardened tissue.

Methods: : Our aim was to evaluate the influence of the laser treatment on the accommodation process in vitro. For the implementation of the gliding planes inside human donor lenses as well as in cat and porcine lenses we used a 100 kHz fs-laser system (wavelength 1040 nm, pulse duration 306 fs, pulse energy 1.3-1.6 µJ). Mechanical and geometrical changes of the lens tissue due to the fs-lentotomy treatment were analyzed.

Results: : The experimental as well as theoretical investigations of the influence of the created gliding planes inside the lens tissue showed an increase in accommodation amplitude after the laser treatment.

Conclusions: : Fs-Laser induced cuts inside the lens tissue lead to a gain in accommodation amplitude of in vitro human donor lenses and cat lenses.

Keywords: accomodation • presbyopia • laser 
© 2009, The Association for Research in Vision and Ophthalmology, Inc., all rights reserved. Permission to republish any abstract or part of an abstract in any form must be obtained in writing from the ARVO Office prior to publication.
Copyright © 2025 Association for Research in Vision and Ophthalmology.
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