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G. J. Parlitsis, G. D. Aaker, M. M. Wessel, M. Cho, D. J. D'Amico, S. Kiss; Ultra-Widefield Angiography Improves the Detection and Classification of Retinal Vascular Occlusions. Invest. Ophthalmol. Vis. Sci. 2010;51(13):287.
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To assess the utility of ultra-widefield angiography in the evaluation of patients with retinal vascular occlusions and to compare the visualized retinal pathology to that seen on seven-standard field imaging.
Patients who suffered a retinal vascular occlusive episode underwent Optomap® dynamic ultra-widefield angiography using the Optos® panoramic P200A imaging system. The extent of retinal ischemia was outlined and quantified using Adobe® Photoshop® software. The total area visualized and the area of ischemia detected using Optos were compared to those obtained using the traditional seven-standard field as specified by the Early Treatment of Diabetic Retinopathy Study.
Seven eyes with retinal vascular occlusions (five veinous occlusions and two arterial occlusions) were imaged. On average, 2.3 times more area of retina was visualized with ultra-widefield imaging compared to seven-standard fields (see figure). Ultra-widefield imaging demonstrated 2.8 times more area of ischemia compared to seven-standard fields in addition to demonstrating peripheral ischemic retina not visible on seven-standard fields in one eye.
Ultra-widefield angiography substantially improves the visualization and quantification of ischemia in patients with retinal vascular occlusive disease. This improved characterization of retinal pathology in retinal vascular occlusions may influence the follow-up and treatment of these eyes.
Figure. Visualization of total retinal area and area of ischemic retina comparing seven-standard fields (left) and ultra-widefield retinal imaging (right).
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