April 2010
Volume 51, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2010
Clinical Assessment of Mirror Artifacts in Spectral Domain Optical Coherence Tomography Device
J. Ho; D. P. E. Castro; L. C. Castro; Y. Chen; J. Liu; J. G. Fujimoto; J. S. Schuman; J. S. Duker
Author Affiliations & Notes
  • J. Ho
    Department of Ophthalmology, Tufts-New England Eye Center, Boston, Massachusetts
  • D. P. E. Castro
    Department of Ophthalmology, Tufts-New England Eye Center, Boston, Massachusetts
  • L. C. Castro
    Department of Ophthalmology, Tufts-New England Eye Center, Boston, Massachusetts
  • Y. Chen
    Department of EECS and RLE, Massachusetts Inst of Technology, Cambridge, Massachusetts
  • J. Liu
    Department of EECS and RLE, Massachusetts Inst of Technology, Cambridge, Massachusetts
  • J. G. Fujimoto
    Department of EECS and RLE, Massachusetts Inst of Technology, Cambridge, Massachusetts
  • J. S. Schuman
    Ophthalmology, UPMC Eye Center/Univ of Pittsburgh, Pittsburgh, Pennsylvania
  • J. S. Duker
    Department of Ophthalmology, Tufts-New England Eye Center, Boston, Massachusetts
  • Footnotes
    Commercial Relationships  J. Ho, None; D.P.E. Castro, None; L.C. Castro, None; Y. Chen, None; J. Liu, None; J.G. Fujimoto, Optovue, Inc., I; Carl Zeiss Meditech, Inc., P; J.S. Schuman, Carl Zeiss Meditech, Inc., F; National Eye Institute, F; SOLX, F; Inspire Pharmaceuticals, Inc., F; Vindico, Inc., C; SLACK, Inc., C; Carl Zeiss Meditech, Inc., P; Bioptigen, Inc., P; Alcon, Inc., R; Carl Zeiss Meditech, Inc., R; Merk & Co., R; Optovue, Inc., R; National Eye Institute, R; J.S. Duker, Carl Zeiss Meditech, Inc., F; Topcon Medical Systems, Inc., F.
  • Footnotes
    Support  Research to Prevent Blindness Challenge Grant, NIH contracts R01-EY011289-24, R01-EY013178-10, R01-EY019029-02, R01-EY013516-07 and AFOSR FA9550-07-1-0101
Investigative Ophthalmology & Visual Science April 2010, Vol.51, 293. doi:
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      J. Ho, D. P. E. Castro, L. C. Castro, Y. Chen, J. Liu, J. G. Fujimoto, J. S. Schuman, J. S. Duker; Clinical Assessment of Mirror Artifacts in Spectral Domain Optical Coherence Tomography Device. Invest. Ophthalmol. Vis. Sci. 2010;51(13):293.

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Abstract

Purpose: : This study investigates the characteristics of a spectral / Fourier domain Optical Coherence Tomography (SD OCT) image artifact known as the "mirror artifact". SD OCT detection produces images symmetrical about the zero delay line. Commercial instruments truncate one side of the image, leaving the remaining half for display. When retinal images cross the zero delay line, the symmetric mirror image on the truncated side will also cross into the scanning range on the displayed portion of the OCT image. Thus, the OCT image appears to be "folded" onto itself. This is known as the mirror artifact. The incidence of this artifact is calculated and correlated to spherical equivalent and central visual acuity (VA), and associated ocular factors and artifact severity are also analyzed.

Methods: : Cirrus HD OCT Macular Cube 512x128 scans taken for a period of one year were analyzed for the presence of mirror artifacts. Severity of artifacts was analyzed by the degree of segmentation breakdown that it caused on the 5x5 macular map (graded from 1/5 to 5/5 of the map). A retrospective medical records review was conducted to note demographics, logMAR VA, ophthalmologic diagnosis, spherical equivalent, and cataract surgery. A random concurrent, comparative subset of patients without artifacts was selected for medical records review for comparison to artifacts group.

Results: : Out of the scans from 1,592 patients, 9.3% of the patient scanned (148 patients, 200 eyes) contained mirror artifacts. Significantly more myopic spherical equivalent (p< 0.001), worse VA (p< 0.001), longer axial lengths (p= 0.004) and higher proportions of mild/high myopia (p< 0.001) was found for patient with than without artifacts. Worse VA is associated with increased artifacts severity (p= 0.04).

Conclusions: : A high incidence of mirror artifacts was found out of all scans analyzed. This artifact was highly correlated with increasing myopic spherical equivalent and worse VA. Improvements in imaging system design may be necessary to resolve this problem in mild/high myopic eyes. Operators should be advised to properly position the retina when scanning non-myopic patients.

Keywords: imaging/image analysis: clinical • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • macula/fovea 
© 2010, The Association for Research in Vision and Ophthalmology, Inc., all rights reserved. Permission to republish any abstract or part of an abstract in any form must be obtained in writing from the ARVO Office prior to publication.
Copyright © 2015 Association for Research in Vision and Ophthalmology.
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