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K. Stafeeva, C. Pan, C. Patel, J. Olson, N. Mandava, S. Oliver, H. Quiroz-Mercado; Importance of Fundus Autofluorescence (FAF) in a Series of Misdiagnosed Cases Involving Choroidal, RPE, and Retinal Pathology. Invest. Ophthalmol. Vis. Sci. 2010;51(13):306.
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© ARVO (1962-2015); The Authors (2016-present)
To show the importance of noninvasive imaging with fundus autofluorescence (FAF) in a series of previously misdiagnosed cases involving choroidal, RPE, and retinal pathology.
Seven cases were retrospectively reviewed. Fundus photos were obtained using the Zeiss FF450 plus camera. Fundus autofluorescence (FAF) images were obtained using the Heidelberg Spectralis HRA+OCT.
All 7 cases were originally misdiagnosed by primary eyecare providers. Fundus autofluorescence (FAF) imaging supplemented the information obtained based on the history and physical examination to establish the diagnosis in all 7 cases. Final diagnoses included bilateral diffuse uveal melanocytic proliferation (BDUMP) (see figure), retinitis pigmentosa ( 2 cases), multifocal choroiditis with panuveitis, acute posterior multifocal placoid pigment epitheliopathy (APMPPE), choroidal hemangioma, and idiopathic macular telangiectasia (MACTEL).
Fundus autofluorescence (FAF) imaging can be a rapid, useful and complementary tool to establish the final diagnosis not only in diseases of RPE but also diseases of choroid and retina. It is a simple and noninvasive method that can lead to earlier diagnosis and treatment.
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