April 2010
Volume 51, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2010
Comparative Analysis of Optical Coherence Tomography Imaging Through Gas Filled Eyes
Author Affiliations & Notes
  • S. P. Shah
    Ophthalmology, Tufts New England Eye Center, Boston, Massachusetts
  • V. Manjunath
    Ophthalmology, Tufts New England Eye Center, Boston, Massachusetts
  • G. Janzen
    Ophthalmology, Tufts New England Eye Center, Boston, Massachusetts
  • A. H. Rogers
    Ophthalmology, Tufts New England Eye Center, Boston, Massachusetts
  • C. Baumal
    Ophthalmology, Tufts New England Eye Center, Boston, Massachusetts
  • E. Reichel
    Ophthalmology, Tufts New England Eye Center, Boston, Massachusetts
  • J. S. Duker
    Ophthalmology, Tufts New England Eye Center, Boston, Massachusetts
  • Footnotes
    Commercial Relationships  S.P. Shah, None; V. Manjunath, None; G. Janzen, None; A.H. Rogers, None; C. Baumal, None; E. Reichel, None; J.S. Duker, Jay S. Duker receives research support from Carl Zeiss Meditech, Inc., Optovue, Inc., and Topcon Medical Systems, Inc., F.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science April 2010, Vol.51, 343. doi:
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      S. P. Shah, V. Manjunath, G. Janzen, A. H. Rogers, C. Baumal, E. Reichel, J. S. Duker; Comparative Analysis of Optical Coherence Tomography Imaging Through Gas Filled Eyes. Invest. Ophthalmol. Vis. Sci. 2010;51(13):343.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To qualitatively assess the ability of commercially available optical coherence tomography (OCT) devices to visualize the macula through a full gas filled eye one day following pars plana vitrectomy (PPV).

Methods: : A retrospective analysis of 16 eyes of 16 patients who underwent OCT imaging on post-operative day 1 following the placement of a C3F8 or SF6 gas bubble was performed. Data collected included sex, age, pre-op diagnosis, pupil size, type and amount of gas fill, lens status, capsule status, degree of corneal edema and anterior chamber inflammation. Images from three commercially available OCT devices were used: StratusOCT3 (Carl Zeiss Meditec, Inc, Dublin, CA, Cirrus HD-OCT (software version 4.0; Carl Zeiss Meditec, Inc., Dublin, CA) and 3D OCT 1000, (TOPCON Medical Systems, New Jersey). A single retinal specialist qualitatively assessed the ability to delineate the contours of both the inner retina/gas interface and the retinal pigment epithelium layer from the line scans.

Results: : There were 10 females and 6 males, with an age range 46 to 87 years. Indications for surgery were retinal detachment in 7 patients and macular hole in 9 patients. SF6 gas (25% or 30%) was used in 8 eyes and C3F8 (15% or 20%) in the other 8. On post-operative day 1, gas fill ranged from 80% - 95%. Pupil size ranged from 4mm to 9mm. Seven eyes were phakic and 9 eyes were pseudophakic, all with PC IOLs.The Cirrus HD-OCT was successfully able to image the retina in 14/16 eyes (87.5%). The Topcon 3D OCT 1000 was able to successfully image the retina in 9 eyes (56.0 %). Eleven eyes were successfully imaged with the Stratus OCT3 (68.8 %). Images were unobtainable on any machine in 2 patients (12.5 %). One of these patients had significant posterior capsule feathering due to gas, and the other had corneal edema.

Conclusions: : OCT imaging through gas filled eyes is feasible on post-operative day 1 in the majority of eyes. Although all three OCT machines were able to image the retina, the Cirrus HD-OCT produced more consistent and higher quality images than the 3D OCT 100 and StratusOCT3. The ability to consistently and accurately image the retina on post-operative day 1 may prove to be an important component of evaluating early closure of macular holes and may serve as a guide to the necessity and/or duration of face down positioning.

Keywords: imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • imaging/image analysis: clinical • macular holes 
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