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S.-Y. Yu, N.-S. Cho, M.-S. Kim, E.-S. Kim, H.-W. Kwak; Drusen in Exudative Age-Related Macular Degeneration. Invest. Ophthalmol. Vis. Sci. 2010;51(13):546.
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To study the prevalence and clinical features of drusen in eyes with exudative age-related macular degeneration (AMD).
Medical records of 103 eyes of 89 patients recorded as same disease code (degeneration of macular and posterior pole) between January 2008 and August 2009 were retrospectively reviewed. Fundus photography, indocyanine green angiography and fundus fluorescein angiography at initial visit were collected.
In these 103 eyes, 69 (68%) eyes had exudative AMD and 34 (32%) eyes had polypoidal choroidal vasculopathy (PCV). In 69 eyes with exudative AMD, 10 (14.5%) showed soft drusen; none of 34 eyes with PCV showed drusen. Comparison of the group of eyes with exudative AMD and drusen with the group with exudative AMD and no drusen revealed followings. Both groups showed improvement of visual acuity, but the group with exudative AMD and drusen had longer period of symptom and better improvement of visual acuity after treatment.
The prevalence of drusen in exudative AMD was low, at 14.5%. Exudative AMD with drusen may take more chronic form.
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