Abstract
Purpose: :
To compare the Goldmann applanation tonometry (GAT) and Dynamic Contour Tonometry (DCT) before, during and after aerobic exercise in normal subjects and glaucoma patients treated with Ganfort and Duotrav.
Methods: :
45 patients [15 Normal subjects, and 30 glaucoma patients (15 treated with Ganfort and 15 treated with Duotrav)] were prospectively enrolled. Intraocular pressure (IOP) by GAT was taken before, just after 40 minutes of aerobic exercise and after 30 minutes of recovering. DCT measurements were taken 5 minutes after GAT. The mean value of 2 measurements from right eye of each patient were considered for calculation. P values < 0.05 were considered statistical significant (t-Test).
Results: :
There was no statistically significant difference between GAT values amongst all groups, except between the IOP in glaucoma patients treated with Ganfort or Duotrav after the recovery period [11.8 ± 0.7 mmHg vs. 12.8 ± 0.8 mmHg]. All groups demonstrated a significant IOP rise from basal IOP after aerobic exercise, but only patients treated Duotrav group showed a poor IOP recovery. Similarly, DCT from Duotrav group showed a poor IOP recovery in comparison to basal IOP. Within the glaucoma group, those patients taking Ganfort had higher IOP after exercise [16.6 ± 0.6 vs. 15.9 ± 0.7 mmHg] compared to those taking Duotrav. In contrast, after rest the values between treated patients were virtually the same [15.1 ± 0.8 vs. 14.9 ± 0.6; p= 0.51].
Conclusions: :
Both GAT and DCT demonstrated a poorer IOP recovering in patients treated with Duotrav in comparison to Ganfort treated patients. Aerobic exercise provoked significant IOP rise in all patients.
Keywords: intraocular pressure