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E. R. Diniz, N. V. Lima, F. N. Kanadani, H. H. Russ, B. P. Figueiredo, T. C. M. Kanadani, A. P. Tupynamba, S. K. Dorairaj; Comparison of Intraocular Pressure by Goldmann Applanation Tonometry vs. Dynamic Contour Tonometry in Normal Subjects and Glaucoma Patients Treated by Ganfort and Duotrav Before, During and After Aerobic Exercise. Invest. Ophthalmol. Vis. Sci. 2010;51(13):581.
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To compare the Goldmann applanation tonometry (GAT) and Dynamic Contour Tonometry (DCT) before, during and after aerobic exercise in normal subjects and glaucoma patients treated with Ganfort and Duotrav.
45 patients [15 Normal subjects, and 30 glaucoma patients (15 treated with Ganfort and 15 treated with Duotrav)] were prospectively enrolled. Intraocular pressure (IOP) by GAT was taken before, just after 40 minutes of aerobic exercise and after 30 minutes of recovering. DCT measurements were taken 5 minutes after GAT. The mean value of 2 measurements from right eye of each patient were considered for calculation. P values < 0.05 were considered statistical significant (t-Test).
There was no statistically significant difference between GAT values amongst all groups, except between the IOP in glaucoma patients treated with Ganfort or Duotrav after the recovery period [11.8 ± 0.7 mmHg vs. 12.8 ± 0.8 mmHg]. All groups demonstrated a significant IOP rise from basal IOP after aerobic exercise, but only patients treated Duotrav group showed a poor IOP recovery. Similarly, DCT from Duotrav group showed a poor IOP recovery in comparison to basal IOP. Within the glaucoma group, those patients taking Ganfort had higher IOP after exercise [16.6 ± 0.6 vs. 15.9 ± 0.7 mmHg] compared to those taking Duotrav. In contrast, after rest the values between treated patients were virtually the same [15.1 ± 0.8 vs. 14.9 ± 0.6; p= 0.51].
Both GAT and DCT demonstrated a poorer IOP recovering in patients treated with Duotrav in comparison to Ganfort treated patients. Aerobic exercise provoked significant IOP rise in all patients.
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