April 2010
Volume 51, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2010
Trabeculectomy With Mitomycin C: Early Postoperative Complication Outcomes
Author Affiliations & Notes
  • F. Shafi
    Birmingham and Midland Eye Centre, Birmingham, United Kingdom
  • P. Agrawal
    Ophthalmology,
    Birmingham and Midland Eye Centre, Birmingham, United Kingdom
  • F. Sii
    Ophthalmology,
    Birmingham and Midland Eye Centre, Birmingham, United Kingdom
  • P. Shah
    Ophthalmology,
    Birmingham and Midland Eye Centre, Birmingham, United Kingdom
    Good Hope Hospital, Birmingham, United Kingdom
Investigative Ophthalmology & Visual Science April 2010, Vol.51, 601. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      F. Shafi, P. Agrawal, F. Sii, P. Shah; Trabeculectomy With Mitomycin C: Early Postoperative Complication Outcomes. Invest. Ophthalmol. Vis. Sci. 2010;51(13):601.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract
 
Purpose:
 

The "ReGAE "(Research into Glaucoma And Ethnicity) Project assesses the surgical outcome of augmented trabeculectomy with mitomycin C in the management of progressive glaucomatous optic neuropathy. This study reports the prevalence of potentially blinding complications in the early post-operative period (within 3 months) from this series of 500 consecutive surgical cases.

 
Methods:
 

Prospective, consecutive, non-comparative case series of 500 eyes undergoing trabeculectomy with mitomycin C. Complications occurring within 3 months of surgery were recorded. Clinically significant early hypotony (CSEH) was defined as an IOP < 6 mmHg during the first post-operative month associated with either a shallow anterior chamber, choroidal detachment or hypotony maculopathy assessed to require intervention (viscoelastic support to anterior chamber, scleral flap suture or conjunctival suture).

 
Results:
 

Data was collected from 500 consecutive surgical cases. Figure 1 shows the complication rates in this series. Higher complication rates were noted in Asian and African-Caribbean patients compared to Caucasians patients. Asian patients experiencing a complication were more likely to require further surgical intervention. Serious visual loss occurred in 0.2% of eyes. Most complications were self-limiting; however, 4.4% of patients needed intervention for CSEH.

 
Conclusions:
 

Low rates of potentially blinding complications in the early postoperative period can be achieved, even in complex surgical cases. Complications were encountered more frequently in African-Caribbean and Asian patients. Asian patients experiencing a complication were more likely to require further surgical intervention. A combination of pre-operative, intra-operative and post-operative techniques can be used to ensure safe surgery.  

 
Keywords: intraocular pressure 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×