Purchase this article with an account.
R. McKean-Cowdin, R. Varma, F. Choudhury, G. Torres, C. M. Patino, S. P. Azen, LALES Group; The Impact of Treatment Related Improvements in Visual Acuity on Item Specific Changes in the NEI-VFQ. The Los Angeles Latino Eye Study (LALES). Invest. Ophthalmol. Vis. Sci. 2010;51(13):960.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
to examine the association between improvements in visual acuity (VA) and item specific changes in the NEI-VFQ in Latinos participating in The Los Angeles Latino Eye Study (LALES).
Data included in this analysis were collected for a population-based cohort of eye disease. Distance visual acuity (VA) was measured during a detailed ophthalmologic examination using standard ETDRS protocol at baseline and a follow-up examination, approximately 4 years later. Vision specific quality of life was assessed at the two time points using the National Eye Institute Visual Function Questionnaire (NEI-VFQ-25). Responses were ranked from "always a problem" (score=0) to "never a problem" (score=100) for 25 task-oriented items related to daily visual functioning. Mean differences in item scores from baseline to follow-up were calculated for 131 participants with a 2 line or greater improvement in VA based on presenting, binocular vision. Paired t-tests were used to calculate 2-sided p-values. Mean differences and effect sizes (ES) for NEI-VFQ item means were calculated.
Over the 4-year follow-up period, we identified 131 participants with a 2 line or greater improvement in presenting binocular VA. Of these, 92 (70%) improved due to treatment with glasses or cataract surgery. For individuals with improved VA, there were 5 items for which we observed statistically significant improvements in scores of 8 points or greater. These questions concerned: (1) ability to read street signs or names of stores (10 point improvement: p<0.001), (2) difficulty in doing work or hobbies that require seeing up close (9.2 point improvement; p=0.002), (3) time spent worrying about eyesight (9.0 point improvement; p=0.03), (4) difficulty reading ordinary print in newspapers (9.3 point improvement; p=0.004), and (5) pain or discomfort in and around eyes (8.2 point improvement; p<0.001). These differences translated into small effect sizes (ES 0.20-0.49) for all 5 items.
Clinically meaningful improvements in VA were associated with significant improvements in quality of life. The greatest improvement were seen for reading at a distance (street signs) or near (books or newsprint), completing work that requires seeing up close, and in the amount worry they had about their vision.
This PDF is available to Subscribers Only