April 2010
Volume 51, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2010
Transcorneal Electrical Stimulation in Patients With Retinitis Pigmentosa
Author Affiliations & Notes
  • M. J. Lopez-Miranda
    Ophthalmology, Asociacion Para Evitar la Ceguera en Mex, Mexico, Mexico
    Ophthalmology, Denver Health, Denver, Colorado
  • D. Robles-Camarillo
    Ophthalmology, Instituto Politecnico Nacional, Mexico, Mexico
  • L. Niño de Rivera y Oyarzaval
    Ophthalmology, Instituto Politecnico Nacional, Mexico, Mexico
  • A. Zavala-Ayala
    Ophthalmology, Asociacion Para Evitar la Ceguera en Mex, Mexico, Mexico
  • C. Cortes-Alcocer
    Ophthalmology, Asociacion Para Evitar la Ceguera en Mex, Mexico, Mexico
  • F. Hernandez-Miranda
    Ophthalmology, Asociacion Para Evitar la Ceguera en Mex, Mexico, Mexico
  • H. Quiroz-Mercado
    Ophthalmology, Denver Health, Denver, Colorado
  • Footnotes
    Commercial Relationships  M.J. Lopez-Miranda, None; D. Robles-Camarillo, None; L. Niño de Rivera y Oyarzaval, None; A. Zavala-Ayala, None; C. Cortes-Alcocer, None; F. Hernandez-Miranda, None; H. Quiroz-Mercado, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science April 2010, Vol.51, 1356. doi:
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    • Get Citation

      M. J. Lopez-Miranda, D. Robles-Camarillo, L. Niño de Rivera y Oyarzaval, A. Zavala-Ayala, C. Cortes-Alcocer, F. Hernandez-Miranda, H. Quiroz-Mercado; Transcorneal Electrical Stimulation in Patients With Retinitis Pigmentosa. Invest. Ophthalmol. Vis. Sci. 2010;51(13):1356.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To describe the effect of transcorneal electrical stimulation (TES) in the best corrected visual acuity (BCVA), visual field and electrophysiological response in patients with retinitis pigmentosa (RP).

Methods: : Descriptive, experimental, prospective study. Patients with clinical diagnosis of RP, with BCVA of 20/200 or better, who were treated with TES therapy were included. We performed a complete ophthalmological examination, BCVA, visual field (Humphrey visual field, Carl Zeiss Meditec Dublin USA) and electroretinogram (ERG) assessment at base line. The TES was delivered by a monopolar contact lens electrode every week for one hour for 30 weeks. Follow-up appointments were performed every week and the studies were repeated every 5 weeks since baseline.

Results: : Twelve patients were included, 5 males, 7 females, Ages ranging from 21 to 73 years-old. Eight patients were diagnosed with classic RP and 4 with Usher syndrome. After stimulation, there was no change in ERG. A minimal increase in visual field was observed. BCVA increased 10 (range) letters but the change was not significant.

Conclusions: : Transcorneal electrical stimulation in eyes of patients with RP resulted in a slightly improved visual field and BCVA, although the change was not statistically significant we propose this treatment to prevent a decrease of best correct visual acuity.

Keywords: retinal degenerations: hereditary • retina • clinical research methodology 
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