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M. Wang, K. Xue, G. Xu, X. Huang, X. Sun; Measurement of Retinal Nerve Fiber Layer Thickness on Retinitis Pigmentosa Patients With GDxECC. Invest. Ophthalmol. Vis. Sci. 2010;51(13):1370.
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© ARVO (1962-2015); The Authors (2016-present)
To observe the thickness of the retinal nerve fiber layer (RNFL) on patients of retinitis pigmentosa (RP) and normal controls measured with GDxECC
20 eyes from 10 RP patients and 40 eyes 20 normal subjects were included. GDxECC(Laser Diagnostic Technologies, Ltd., San Diego, CA) measured the thickness of RNFL in the peripapillary area in all subjects. TSNIT parameters including TSNIT average, superior average, inferior average, TSNIT standard deviation, inter-eye symmetry and NFI were obtained with GDxECC.
For GDxECC in RP patients and controls, TSNIT averages were 66.17±5.78 and 56.92±4.72. Superior averages were 81.66±8.76 and 70.81±7.32. Inferior averages were 83.06±8.67 and 68.34±6.89. TSNIT standard deviations were 28.72±5.22 and 24.65±4.11. Inter-eye symmetries were 0.85±0.11 and 0.87±0.09. NFIs were 8.17±8.10 and 16.74±8.05. The difference of TSNIT average, superior average, inferior average, TSNIT standard deviation and NFI had statistical significance (p<0.001).
The thickness of RNFL measured with GDxECC was significantly thicker in RP patients than in controls. The results provide the RNFL thickness information for investigating the mechanism of this phenomenon. 1. Hood et al IOVS (2009); 2. Walia and Fishman IOVS (2008)
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