April 2010
Volume 51, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2010
Which Examination Duration is Required for a Sufficient Recording Quality in Multifocal ERG?
Author Affiliations & Notes
  • B. A. Mazinani
    Ophthalmology, University of Aachen, Aachen, Germany
  • A. K. Vehr
    Ophthalmology, University of Aachen, Aachen, Germany
  • Y.-L. Lin
    Ophthalmology, University of Aachen, Aachen, Germany
  • G. F. Roessler
    Ophthalmology, University of Aachen, Aachen, Germany
  • N. Plange
    Ophthalmology, University of Aachen, Aachen, Germany
  • P. Walter
    Ophthalmology, University of Aachen, Aachen, Germany
  • Footnotes
    Commercial Relationships  B.A. Mazinani, None; A.K. Vehr, None; Y.-L. Lin, None; G.F. Roessler, None; N. Plange, None; P. Walter, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science April 2010, Vol.51, 1481. doi:
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    • Get Citation

      B. A. Mazinani, A. K. Vehr, Y.-L. Lin, G. F. Roessler, N. Plange, P. Walter; Which Examination Duration is Required for a Sufficient Recording Quality in Multifocal ERG?. Invest. Ophthalmol. Vis. Sci. 2010;51(13):1481.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To improve the signal-to-noise ratio in multifocal ERG recordings, an as long as possible examination duration (using a long M-sequence or by repeating short M-sequences) is desirable. Purpose of this study was to test, how long an examination duration is sufficient to obtain an acceptable recording quality.

Methods: : 16 healthy subjects underwent repeated multifocal ERG testing (Roland Consult, Wiesbaden, Germany) with a resolution of 61 hexagons using short M-sequences with 512 steps of 47 s duration for stimulation. The retest-repeatability of examinations with 1 up to 8 averages of 47-s-sequences were calculated using coefficients of variation.

Results: : The retest-repeatability improved with increasing number of averages expressed by decreasing coefficients of variation from 1 up to 8 averages: 0.36, 0.22, 0.2, 0.18, 0.14, 0.15, 0.13 and 0.13. Whereas the difference of the repeatability between 1, 2, 3 and 4 averages on the one hand and 8 averages on the other were significant, no significant difference could be noticed after the fifth average compared to 8 averages.

Conclusions: : Our study shows that in multifocal ERG recordings using short M-sequences with a resolution of 61 hexagons more than 5 averages of 47-s-sequences do not improve the repeatability of the results. Thereby examination time and exposure of the patient can be limited by restricting to 5 averages without losing recording quality.

Keywords: electroretinography: clinical 
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