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B. A. Mazinani, A. K. Vehr, Y.-L. Lin, G. F. Roessler, N. Plange, P. Walter; Which Examination Duration is Required for a Sufficient Recording Quality in Multifocal ERG?. Invest. Ophthalmol. Vis. Sci. 2010;51(13):1481.
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To improve the signal-to-noise ratio in multifocal ERG recordings, an as long as possible examination duration (using a long M-sequence or by repeating short M-sequences) is desirable. Purpose of this study was to test, how long an examination duration is sufficient to obtain an acceptable recording quality.
16 healthy subjects underwent repeated multifocal ERG testing (Roland Consult, Wiesbaden, Germany) with a resolution of 61 hexagons using short M-sequences with 512 steps of 47 s duration for stimulation. The retest-repeatability of examinations with 1 up to 8 averages of 47-s-sequences were calculated using coefficients of variation.
The retest-repeatability improved with increasing number of averages expressed by decreasing coefficients of variation from 1 up to 8 averages: 0.36, 0.22, 0.2, 0.18, 0.14, 0.15, 0.13 and 0.13. Whereas the difference of the repeatability between 1, 2, 3 and 4 averages on the one hand and 8 averages on the other were significant, no significant difference could be noticed after the fifth average compared to 8 averages.
Our study shows that in multifocal ERG recordings using short M-sequences with a resolution of 61 hexagons more than 5 averages of 47-s-sequences do not improve the repeatability of the results. Thereby examination time and exposure of the patient can be limited by restricting to 5 averages without losing recording quality.
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