April 2010
Volume 51, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2010
Change in Ocular Biometry Over Five Years in an Older Population. Preliminary Findings
Author Affiliations & Notes
  • B. E. K. Klein
    Ophthalmology and Visual Sciences, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin
  • R. Klein
    Ophthalmology and Visual Sciences, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin
  • K. E. Lee
    Ophthalmology and Visual Sciences, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin
  • T. Y. Wong
    Singapore Eye Research Institute, National University of Singapore, Singapore, Singapore
  • Footnotes
    Commercial Relationships  B.E.K. Klein, None; R. Klein, None; K.E. Lee, None; T.Y. Wong, None.
  • Footnotes
    Support  Supported by National Institutes of Health grant EY06594 and, in part, by Research to Prevent Blindness (R. Klein, BEK Klein, Senior Scientific Investigator Awards, New York, NY).
Investigative Ophthalmology & Visual Science April 2010, Vol.51, 1706. doi:
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    • Get Citation

      B. E. K. Klein, R. Klein, K. E. Lee, T. Y. Wong; Change in Ocular Biometry Over Five Years in an Older Population. Preliminary Findings. Invest. Ophthalmol. Vis. Sci. 2010;51(13):1706.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To determine whether there are changes in axial length, corneal curvature and anterior chamber depth in older adults over a five year interval.

Methods: : Measures were determined using a standardized instrument on participants in the Beaver Dam Eye Study during the 2003-2005 examination (n=1962) and during the ongoing follow-up examination five years later (n=776). The age range at the 2003-2005 examination was 58-100 years. Besides biometry measures, there are data on education level, ocular history, height and nuclear cataract as graded from slit lamp photographs.

Results: : There were 776 persons with biometry measures at both visits. The average changes in biometry were: .035 ± .55 mm for axial length (longer), -.001 ± .04 mm curvature for mean corneal curvature (flatter), and .08 ± .49 mm (deeper) for anterior chamber depth. In multivariable models including age, sex and height, only sex was significantly associated with change in axial length. Not age nor sex nor height were associated with change in mean corneal curvature, and age was associated with change in anterior chamber depth. Presence of nuclear cataract attenuated the age effect on anterior chamber depth. Education had no effect in any models.

Conclusions: : There appears to be little change in ocular biometry over a 5 year interval in older adults. This is important because it suggests that changes in refraction and vision that occur with age are likely not related to changes in biometry.

Keywords: aging • clinical (human) or epidemiologic studies: prevalence/incidence • refraction 
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