Purchase this article with an account.
L. S. Kearns, A. W. Hewitt, J. B. Ruddle, O. Bigault, S. E. Staffieri, P. Sanfillipo, N. G. Martin, C. J. Hammond, T. L. Young, D. A. Mackey; Up to What Age is a Cyclopleged Refraction Required? Results From the Twins Eye Study Tasmania(TEST). Invest. Ophthalmol. Vis. Sci. 2010;51(13):1716.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
As children have a large amplitude of accommodation, cycloplegic refraction is routinely used in pediatric ophthalmic practice. The aim of this study was to determine the age up to which cycloplegia is required for accurate refraction.
Subjects were recruited from the Twin Eye Study in Tasmania and the Brisbane Adolescent Twin Study. In each participant, refractive error was measured using a Humphrey 598 Autorefractor, before and after cycloplegia. Subjects were excluded if they had undergone cataract surgery or had anterior segment disease. Analyses were restricted to people aged between 13 and 26 years. Generalised estimating equations (GEE) were used to model each of the spherical equivalence difference against age. Each GEE was clustered by family relationship and zygosity. Data are presented as the mean±SD.
Data were available from 1297 people from 597 families. The mean difference between pre- and post cycloplegia spherical equivalent (SE) decreased from 0.36±0.41D in the 13 year olds to 0.06±0.50D in people aged 25 years. After adjusting for zygosity, the difference between pre- and post cycloplegia refraction was significant in all age groups up until the age of 20 years.
Our data suggests that cycloplegic refraction should be performed up until the age of 20 years. This finding has direct implications for population-based studies of refraction.
This PDF is available to Subscribers Only