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H. Omata, K. Mori, D. Imai, S. Yoneya; Normative Values for Foveolar, Macular and Peripheral Retinal Thickness by Spectral-Domain Optical Coherence Tomography. Invest. Ophthalmol. Vis. Sci. 2010;51(13):1770.
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To describe normative data for the foveolar, macular and peripheral retinal thickness with spectral-domain optical coherence tomography (SD-OCT) in Japanese normal subjects.
A total of 30 healthy eyes from 30 subjects, age ranging 12 to 80 years (48 ± 22, mean ± SD) were included in this study. Inclusion criteria were best corrected visual acuity of 20/20 or better, refractive error from -5.0 to +3.0 diopter, no ocular diseases and normal intraocular pressure. We measured retinal thickness at a central foveola and retinal regions 1, 3, and 9 mm from foveola in 8 directions of nasal, superior nasal, superior, superior temporal, temporal, inferior temporal, inferior and inferior nasal using SD-OCT (Cirrus, Carl Zeiss Meditec).
The mean foveolar thickness was 189.3 ±15.9 µm. The retinal thickness at 1 mm from central fovea in directions of superior nasal, superior temporal, inferior temporal and inferior nasal was 328.4±18.4, 320.7±15.1, 319.8±22.1 and 319.7µm, respectively. The retinal thickness at 9 mm in the same directions was 197.3±14.4, 177.5±14.1, 173.4±14.3 and 180.8±18.2 µm. The retinal thickness in the superior nasal region at 9 mm was thickest among other measured regions (p=2.65×10-5, ANOVA). There was no significant correlation between age and retinal thickness of each measured region (p>0.05, Peason’s correlation coefficient test).
Normative values for foveolar, macular and peripheral retinal thickness of Japanese Asian subjects were measured and described precisely. Grobal and regional differences were presented. Since racial differences of OCT measurement have been reported, our data proposes the guidelines for normative retinal thickness in Asian subjects.
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