April 2010
Volume 51, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2010
A Silicone Hydrogel Contact Lens Produced Less Myopia Progression Than Single Vision Spectacles in Chinese Children Over a 6 Month Period
Author Affiliations & Notes
  • P. Lazon De La Jara
    Institute for Eye Research, Sydney, Australia
    Vision CRC, Sydney, Australia
  • P. Sankaridurg
    Institute for Eye Research, Sydney, Australia
    Vision CRC, Sydney, Australia
  • A. Ho
    Institute for Eye Research, Sydney, Australia
    Vision CRC, Sydney, Australia
  • A. Martinez
    Institute for Eye Research, Sydney, Australia
    Vision CRC, Sydney, Australia
  • L. Donovan
    Institute for Eye Research, Sydney, Australia
    Vision CRC, Sydney, Australia
  • E. L. Smith, III
    College of Optometry, University of Houston, Houston, Texas
  • X. Chen
    Zhongshan Ophthalmic Centre, Sun Yat-Sen University, Guangzhou, China
  • J. Ge
    Zhongshan Ophthalmic Centre, Sun Yat-Sen University, Guangzhou, China
  • B. Holden
    Institute for Eye Research, Sydney, Australia
    School of Optometry and Vision Science, University of New South Wales, Sydney, Australia
  • The Vision CRC Myopia Control Study Group
    Institute for Eye Research, Sydney, Australia
  • Footnotes
    Commercial Relationships  P. Lazon De La Jara, Institute for Eye Research, E; WO2009/129528A1, P; P. Sankaridurg, Institute for Eye Research, E; US2007/0296916A1, US2009/129528A1, US2009/0122264, P; A. Ho, Institute for Eye Research, E; US7025460B2, US2007/0296916A1, US2009/129528A1, US2009/0122264, P; A. Martinez, Institute for Eye Research, E; WO2009/129528A1, US2009/0122264, P; L. Donovan, Institute for Eye Research, E; E.L. Smith, III, US7025460B2, US2007/0296916A1, US2009/129528A1, P; X. Chen, None; J. Ge, None; B. Holden, Institute for Eye Research, E; US7025460B2, US2009/0122264, WO2009/129528A1, US2007/0296916A1, P.
  • Footnotes
    Support  Funded by the Institute for Eye Research, CIBA Vision, and the Australian Government CRC Program.
Investigative Ophthalmology & Visual Science April 2010, Vol.51, 2198. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      P. Lazon De La Jara, P. Sankaridurg, A. Ho, A. Martinez, L. Donovan, E. L. Smith, III, X. Chen, J. Ge, B. Holden, The Vision CRC Myopia Control Study Group; A Silicone Hydrogel Contact Lens Produced Less Myopia Progression Than Single Vision Spectacles in Chinese Children Over a 6 Month Period. Invest. Ophthalmol. Vis. Sci. 2010;51(13):2198.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose: : To compare myopia progression in Chinese children after 6 months wear of single vision spectacles (SPL) and single-vision silicone hydrogel contact lens (SHCL).

Methods: : The myopia progression of 33 children wearing SPL and 43 children wearing SHCL (Lotrafilcon B, CIBA Vision) on a daily-wear basis, was compared at 6 months. Cycloplegic central autorefraction, peripheral refraction (Shin Nippon NVision K-5001) along the horizontal meridian (20°, 30° and 40° nasal and temporal fields) and axial length (AL) with IOLMaster were measured at the same institution by the same investigators. Inclusion criteria included age from 7 to 14 y/o; baseline refraction (Rx) from -0.75D to -3.50D sphere; and cylinder ≤ 0.50D. Multivariate analysis was performed to test for effect of lens type, after adjusting for parental myopia, gender, age and Rx on myopia progression. The combined data from the two groups were used to analyse the relationship between myopia progression and peripheral refraction at each field angle.

Results: : After adjusting for parental myopia, gender, age and Rx, myopia progression was 38% less (p<0.001) for SHCL (-0.37±0.29D) than SPL (-0.60±0.29D). Similarly, AL increase was 44% less (p<0.001) for SHCL (0.14±0.12 mm) than SPL (0.25±0.12 mm). Myopia progression was significantly affected by baseline age (p=0.031) but not by Rx or gender (p>0.05). Analysis of refraction results showed that SPL produced greater peripheral hyperopic defocus than SHCL for all field angles except for 40° nasal field (temporal retina).

Conclusions: : The faster myopia progression observed for SPL may have been due to higher amounts of relative peripheral hyperopia with SPL than SHCL. Longer term follow-up is in progress.

Clinical Trial: : www.chictr.org 00000029 & 00000232

Keywords: myopia • contact lens • spectacle lens 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×