Correlation Between Angiographic and OCT Findings in Parafoveal Telangiectasia

Abstract

Purpose: : To report and correlate the optical coherence tomography (OCT) and fluorescein angiography (FA) findings of parafoveal telangiectasia (PFT).

Methods: : A retrospective chart review was performed of all consecutive patients diagnosed with PFT between 2001 and 2007.Visual acuity, fundus biomIcroscopy, FA and OCT findings were recorded.

Results: : Twenty one patients with PFT were included; 3 were type I and 18 were type II. Grade I OCT findings (normal or small slit-like spaces) were found in 15 eyes. Grade II OCT findings (large cysts in the inner or outer retina without retinal thickening) were found in 17 eyes. Grade III OCT findings (cystoid macular edema) were found only in 5 eyes . Two eyes developed choroidal neovascularisation with chorioretinal anastomosis. Fluorescien angiography showed diffuse parafoveal late leakage in all patients. Seventeen eyes had microaneurysms on FA with intense late focal hyperfluorescence and enlargement of the foveal avascular zone (focal leak). Two of the 15 eyes with grade I OCT findings (13%) had focal leak; 10 of the eyes with grade II OCT findings (59%) had focal leak; and all of the eyes with grade III OCT findings showed focal leak (p= 0.001). Visual acuity was not found to correlate with either FA or OCT characteristics.

Conclusions: : We found statistically significant correlation between the presence of microaneurysms and intense late focal leakage with larger cysts without thickening and also with cystoids macular edma. Therapeutic implications of our findings will be discussed.

Keywords: macula/fovea • degenerations/dystrophies • edema