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M. Harasawa, A. F. Bordon, G. Z. Ramos, V. C. C. Afonso, L. F. Q. S. da Silveira, G. A. B. Pereira, A. Raskin, C. Moreira; Analysis of Central Macular Thickness Before and After Laser Photocoagulation for Diabetic Macular Edema. Invest. Ophthalmol. Vis. Sci. 2010;51(13):2298.
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To compare the central macular thickness by optical coherence tomography (Stratus -OCT) before and 1 to 2 hours after macular laser photocoagulation in patients with diabetic macular edema.
Non interventional, prospective study of twelve patients (13 eyes) with diabetic macular edema that were treated with focal or grid macular laser photocoagulation (green laser Eye Light 532, Alcon Laboratory). All patients underwent to a complete ophthalmological examination, including slit lamp biomicroscopy, fundoscopy, and indirect ophthalmoscopy. Before treatment, an OCT3 imaging (fast macular thickness map) was performed in each eye and was repeated 1 to 2 hours after laser treatment.
Twelve patients with mean age of 63.1 years-old (range, 47-77years), 4 female and 8 were male, 4 were right eyes and 9 were left eyes. All patients had clinical and angiographic diagnosis of diabetic macular edema. The mean central macular thickness before laser was 259.9 microns and after laser was 281.9 microns. None patient complained of decreased visual acuity 1-2 hours after the laser treatment. There was statistic significant increase of 22.0 microns (p=0.025).
This study demonstrates that laser photocoagulation produces macular thickening of the central retinal area shortly after the procedure, although was not clinically noted by the patients.
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