April 2010
Volume 51, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2010
Long-Term Trends in Intraocular Pressure After Pars Plana Vitrectomy
Author Affiliations & Notes
  • M. Lalezary
    Ophthalmology, Vanderbilt Eye Institute, Nashville, Tennessee
  • S. J. Kim
    Ophthalmology, Vanderbilt Eye Institute, Nashville, Tennessee
  • K. Jiramongkolchai
    Ophthalmology, Vanderbilt Eye Institute, Nashville, Tennessee
  • F. M. Recchia
    Ophthalmology, Vanderbilt Eye Institute, Nashville, Tennessee
  • A. Agarwal
    Ophthalmology, Vanderbilt Eye Institute, Nashville, Tennessee
  • P. Sternberg
    Ophthalmology, Vanderbilt Eye Institute, Nashville, Tennessee
  • Footnotes
    Commercial Relationships  M. Lalezary, None; S.J. Kim, None; K. Jiramongkolchai, None; F.M. Recchia, None; A. Agarwal, None; P. Sternberg, None.
  • Footnotes
    Support  Unrestricted grant from Research to Prevent Blindness
Investigative Ophthalmology & Visual Science April 2010, Vol.51, 2562. doi:
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    • Get Citation

      M. Lalezary, S. J. Kim, K. Jiramongkolchai, F. M. Recchia, A. Agarwal, P. Sternberg; Long-Term Trends in Intraocular Pressure After Pars Plana Vitrectomy. Invest. Ophthalmol. Vis. Sci. 2010;51(13):2562.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Introduction: : Objective: To evaluate the effect of vitrectomy on intraocular pressure (IOP).

Design: : Retrospective Cohort Study.

Participants: : One hundred and one eyes of 101 patients undergoing non-emergent vitrectomy surgery.

Methods: : Medical records were reviewed for rates of open-angle glaucoma (OAG), increased IOP > 4 mm Hg from baseline, change in IOP from baseline, and cataract formation. Preoperative and last measured IOPs were recorded. Baseline risk characteristics including lens status and diabetes were analyzed.

Results: : Mean follow-up was 49 months (range 12 to 105). Mean baseline IOP was 15.3 mm Hg and mean final IOP was 15.8 mm Hg (P = 0.3). At final exam, 35 eyes had a decrease in IOP from baseline while 14 had no change and 52 had an increase in IOP. Four study eyes were newly diagnosed with ocular hypertension. No study eyes developed OAG or required medical, laser, or surgical treatment for glaucoma. Incidence of increased IOP > 4 was 7% at 4 years and 34% at 8 years. Sub-group analysis of 66 comparing study eyes with non-vitrectomized fellow eyes demonstrated no significant difference in rates of increased IOP > 4 (P = 0.85). Neither diabetes nor pseudophakia were associated with significantly increased IOP.

Main Outcome Measures: : Incidence of OAG, increased IOP > 4, and change in IOP.

Conclusions: : In this series, vitrectomy does not appear to increase IOP or rates of OAG even after removal of the crystaline lens.

Keywords: intraocular pressure • vitreoretinal surgery • clinical (human) or epidemiologic studies: prevalence/incidence 
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