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S. Cayette, K. Julian, C. Fardeau, C. Terrada, C. Aknin, B. Bodaghi, P. Le Hoang, N. Cassoux; Pars Plana Vitrectomy in the Management of Uveitis-Related Epiretinal Membrane. Invest. Ophthalmol. Vis. Sci. 2010;51(13):2571.
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To describe anathomical and functional outcomes of pars plana vitrectomy for uveitis-related epiretinal membrane (ERM) in comparison to idiopathic ones.
Retrospective, interventional, comparative, case series. Files from patients who underwent three-port pars plana vitrectomy for the management of ERM were reviewed for best-corrected visual acuity (BCVA), metamorphosia, optical coherence tomography (OCT) findings and recurrences. Data from uveitis-related ERM were compared to idiopathic ones.
Fourteen uveitis-related ERM cases and twenty-six idiopathic ones were included. All patients underwent three-port 20 Gauges pars plana vitrectomy when visual acuity was ≤ 5/10 ; all uveitic cases achieved at least three months of no-inflammation before surgery. Post-operative BCVA ≥ 4/10 was achieved by 35,7 % of patients with uveitis-related ERM and 73% of their idiopathic counterparts. Metamorphopsia disappeared in all cases of idiopathic ERM but in 41% of uveitic cases. OCT macular scans showed a reduction in macular edema of more than 50% (compared with the basal one) in 78,5% of uveitis-related cases and 90,4% of idiopathic ones. Recurrence occurred in 21,4% of uveitic cases and 0% of idiopathic ones. Median follow up was 54,5 months (1-108).
Pars plana vitrectomy showed better functional and anatomical results in cases of idiopathic ERM than their uveitic counterparts. Recurrent inflammation may preclude higher rates of improvement in ERM secondary to uveitis.
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